Scribd Logo
Upload

Welcome to Scribd!

  • GENETIKA MOLEKULER Dari Lanna

    Uploaded by

    Lanna Harumiya
    10 views2 pages
    This document discusses hemophilia, a sex-linked genetic disorder characterized by impaired blood clotting. It contains the following key points: 1. Hemophilia A is the most common type of hemophilia, accounting for about 80% of cases, and is caused by a lack of clotting factor VIII. 2. Hemophilia is inherited through the X chromosome, so it is more common and severe in males, who have only one X chromosome. 3. The document also contains diagrams illustrating different types of enzyme inhibition plots, showing how the maximum reaction rate (Vmax) and Michaelis constant (Km) are affected by competitive, noncompetitive, and uncompetitive

    Original Description:

    Molecular Genetic, Genetical Molecule, Moe, Moe, Moeeru

    Original Title

    GENETIKA MOLEKULER dari Lanna

    Copyright

    © © All Rights Reserved

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document discusses hemophilia, a sex-linked genetic disorder characterized by impaired blood clotting. It contains the following key points: 1. Hemophilia A is the most common type of hemophilia, accounting for about 80% of cases, and is caused by a lack of clotting factor VIII. 2. Hemophilia is inherited through the X chromosome, so it is more common and severe in males, who have only one X chromosome. 3. The document also contains diagrams illustrating different types of enzyme inhibition plots, showing how the maximum reaction rate (Vmax) and Michaelis constant (Km) are affected by competitive, noncompetitive, and uncompetitive

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    10 views2 pages

    GENETIKA MOLEKULER Dari Lanna

    Uploaded by

    Lanna Harumiya
    This document discusses hemophilia, a sex-linked genetic disorder characterized by impaired blood clotting. It contains the following key points: 1. Hemophilia A is the most common type of hemophilia, accounting for about 80% of cases, and is caused by a lack of clotting factor VIII. 2. Hemophilia is inherited through the X chromosome, so it is more common and severe in males, who have only one X chromosome. 3. The document also contains diagrams illustrating different types of enzyme inhibition plots, showing how the maximum reaction rate (Vmax) and Michaelis constant (Km) are affected by competitive, noncompetitive, and uncompetitive

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 2

    female

    normal male
    hemophilic male
    female
    normal male
    hemophilic male
    GENETIKA MOLEKULAR
    PEDIGREE OF HEMOFHILIA IN ONE
    FAMILY
    HEMOPHILIA
    Hemophilia - A sex linke !ene"i#
    iso$e$ in %hi#h &loo #lo""in! is
    e'i#ien" (
    Hemophilia A - la#k o' an"ihemophili#
    !lo&)lin (
    Mos" #ommon "*pe +,-. o' #ases/(
    Hemophilia 0 - e'e#" in "h$om&o-plas"i#
    #omponen" - a mile$ 'o$m o' "he isease(
    1ex linke - "$ai" 'o)n on 2 #h$omo-
    some(
    3RHOMO1OME1
    4( En5im non ')n!sional
    - Tiak melak)kan ')n!si 'isiolo!is alam
    a$ah
    - Kaa$ alam a$ah sampai se6)"a kali lipa"
    le&ih $enah a$i i 6a$in!an
    K
    m
    Enzyme Inhibition (Plots)
    Competitive Non-competitive Uncompetitive
    D
    i
    r
    e
    c
    t

    P
    l
    o
    t
    s
    D
    o
    u
    b
    l
    e

    R
    e
    c
    i
    p
    r
    o
    c
    a
    l
    V
    max
    V
    max
    K
    m
    K
    m
    [S], m
    v
    o
    [S], m
    v
    o
    I I I I
    K
    m
    [S], m
    V
    max
    I I
    K
    m

    V
    max
    ! V
    max
    !
    V
    max
    unchan"e#
    K
    m
    increase#
    V
    max
    #ecrease#
    K
    m
    unchan"e#
    $oth V
    max
    % K
    m
    #ecrease#
    I I
    &'[S] 1/K
    m
    1/v
    o
    &' V
    max
    I I
    ()o parallel
    lines
    I I
    Intersect
    at * axis
    1/v
    o
    &' V
    max
    &'[S] 1/K
    m
    &'[S] 1/K
    m
    &' V
    max
    1/v
    o
    Intersect
    at + axis
    , K
    m

    -uan" R. (/001) $2basics

    You might also like