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Drug Sheets for Clinical

Drug Sheets for Clinical

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Published by jvdeyk

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Published by: jvdeyk on Nov 10, 2009
Copyright:Attribution Non-commercial


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ASA (apirin)
– antipyretic, nonopiod analgesicIndications: inflammatory disorders including RA, OA. Mild to moderate pain. Fever.
: prophylaxis of ischemic attacks and MI.Actions: - produce analgesia and reduce inflammation and fever by inhibiting theproduction of prostaglandins
(only aspirin decreases platelet aggregation)Side effects:
GI bleeding, dyspepsia, epigastric distress, nausea, exfoliative dermatitis, stevens- johnson syndrome, toxic epidermal necrolysis
Digoxin (antiarrhythmics, inotropics)
Indications: treatment of CHF. Tachyarrhythmias: atrial fibrillation and atrial flutter,paroxysmal atrial tachycardiaAction: increases force of myocardial contraction. Prolongs refractory period of AVnode. Decreases conduction through the SA and AV nodes Therapeutic effects: increased cardiac output (positive inotropic effect) and slowingthe hrt rate (negative chronotropic effect)
Side effects:
Arrhythmias; fatigue, bradycardia, anorexia, nausea, vomiting
Nursing Implications:
Monitor apical pulse for one full minute before administration. Withhold dose andnotify physician if pulse rate is <60 bpm in an adultMonitor ECG throughout IV administration and 6 hrs after each dose. Notify healthcare professional if bradycardia or new arrhythmias occur.Narrow therapeutic range.
Plavix (Clopidogrel) – (antiplatelet agents)
Indications: Reduction of atherosclerotic events in pts at risk for such eventsincluding recent MI, acute coronary syndrome, stroke, or peripheral vasculardiseasesAction: inhibits platelet aggregation by irreversibly inhibiting the binding of ATP toplatelet receptors
 Therapeutic effects: Decreased occurrence of atherosclerotic events in patients atriskSide effects:GI bleeding, bleeding, neutropenia, thrombocytopenic purpura (rare)Nursing implications:Monitor pt. for signs of thrombotic thrombocytic purpura (thrombocytopenia,microangiopathic hemolytic anemia, neurologic findings, renal dysfunction, fever)Monitor bleeding time during therapy and CBC with differential and platelet countDalteparin, Enoxaparin (anticoagulants)Indications: prevention of venous thromboembolism (deep vein thrombosis) and/orpulmonary embolism or surgical or medical pts.Action: Potentiate the inhibitory effects of antithrombin on factor Xa and thrombin. Therapeutic effects: prevention of thrombus formationNursing Implications:Assess for signs of bleeding and hemorrhage (bleeding gums; nosebleed; unusualbruising; black, tarry stools; hematuria; fall in hematocrit or BP; bleeding fromsurgical site.
Metoprolol (antianginals, antihypertensive) (betablockers)
Indications: Hypertension. Angina pectoris. Prevention of MI and decreasedmortality in pts with recent MI. Management of stable, symptomatic heart failuredue to ischemic, hypertensive and cardiomyopathic originActions: Blocks stimulation of beta1- adrenergic receptors. Therapeutic effects: Decreased BP and hrt rate. Decreased frequency of attacks of angina pectoris. Decreased rate of cardiovascular mortality and hospitalization inpts with heart failure.Side effects: bradycardia, CHF, pulmonary edema, erectile dysfunction.Nursing Implications:Monitor vital signs and ECG every 5-15 mins during and for several hrs afterparenteral administration. If heart rate is <40bpm, especially if cardiac output isalso decreased, adminster atropine IV

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