– antipyretic, nonopiod analgesicIndications: inflammatory disorders including RA, OA. Mild to moderate pain. Fever.
: prophylaxis of ischemic attacks and MI.Actions: - produce analgesia and reduce inflammation and fever by inhibiting theproduction of prostaglandins
(only aspirin decreases platelet aggregation)Side effects:
GI bleeding, dyspepsia, epigastric distress, nausea, exfoliative dermatitis, stevens- johnson syndrome, toxic epidermal necrolysis
Digoxin (antiarrhythmics, inotropics)
Indications: treatment of CHF. Tachyarrhythmias: atrial fibrillation and atrial flutter,paroxysmal atrial tachycardiaAction: increases force of myocardial contraction. Prolongs refractory period of AVnode. Decreases conduction through the SA and AV nodes Therapeutic effects: increased cardiac output (positive inotropic effect) and slowingthe hrt rate (negative chronotropic effect)
Arrhythmias; fatigue, bradycardia, anorexia, nausea, vomiting
Monitor apical pulse for one full minute before administration. Withhold dose andnotify physician if pulse rate is <60 bpm in an adultMonitor ECG throughout IV administration and 6 hrs after each dose. Notify healthcare professional if bradycardia or new arrhythmias occur.Narrow therapeutic range.
Plavix (Clopidogrel) – (antiplatelet agents)
Indications: Reduction of atherosclerotic events in pts at risk for such eventsincluding recent MI, acute coronary syndrome, stroke, or peripheral vasculardiseasesAction: inhibits platelet aggregation by irreversibly inhibiting the binding of ATP toplatelet receptors