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Scleroderma • Progressive Systemic Sclerosis:Inflammation, Vascular Sclerosis, Fibrosis of Skin

Scleroderma • Progressive Systemic Sclerosis:Inflammation, Vascular Sclerosis, Fibrosis of Skin

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Published by hollyu

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Published by: hollyu on Nov 19, 2009
Copyright:Attribution Non-commercial

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05/11/2014

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 Scleroderma
Progressive systemic sclerosis
:
Inflammation, Vascular sclerosis, Fibrosis of skin andviscera
Tissue edema
Some Pts have CREST syndrome, C: calcinosis, R: Raynaud’s phenomenon, E:esophageal hypomotality, S: scleroderma, T: Telengectesia
F>M, Age 20-40
Pregnancy
the progression of the disease in 50% of the Pt.
 A:
flexion contracture
difficult airway due to limited mouth opening,
motility
 ,
LOStone
GERD
need RSI
 B:
A major cause of M&M, Chronic aspiration, Diffuse lung fibrosis
restrictive lungdisease,
diffusion capacity
C:
risk of 
IHD
, fibrosis of the conductive system
arrhythmia
, cardiomyopathy
CHF
,systemic and pulmonary HTN, pericarditis
effusion
tamponade, with systemic HTN
 
intravascular volume
hypotension , Raynaud’s phenomenon in 70%
risk of ischemiawith art-line
CNS:
peripheral and cranial nerve neuropathy
o
 Eye:
conjunctivitis and corneal abrasion

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