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Phenylalanine and tyrosine metabolism (18 Oct)

Phenylalanine and tyrosine metabolism (18 Oct)

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Published by: api-19824406 on Dec 04, 2009
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03/18/2014

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Phenylalanine and TyrosinePhenylalanine and TyrosineMetabolismMetabolism
Dr. Mohammad AkramDr. Mohammad Akram
 
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PhenylalaninePhenylalanine
PhenylalaninePhenylalanineisisananessentialessentialaminoaminoacidacid (building(buildingblockblockfoforproteinsproteinsininthethebody)body)..ItIt isisessentialessentialtotohumanhumanhealthhealthbutbutcannotcannotbebe manufacturedmanufacturedbybythethebodybody..FoForthisthis reason,reason,phenylalaninephenylalaninemustmustbebeobtainedobtained fromfromfoodfood..TheThebodybodyconvertsconverts phenylalaninephenylalanineintointotyrosine,tyrosine,anotheanotheraminoamino acidacidessentialessentialfoformakingmakingproteins,proteins,brainbrain chemicalschemicalsincludingincludingdopaminedopamineandand norepinephrine,norepinephrine,andandthyroidthyroidhormoneshormones..
 
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Phenylalanine and TyrosinePhenylalanine and TyrosineCatabolismCatabolism
Phenylalanine normally has only two fates:Phenylalanine normally has only two fates:incorporation into polypeptide chains, andincorporation into polypeptide chains, andproduction of tyrosine via theproduction of tyrosine via thetetrahydrobiopterintetrahydrobiopterin--requiringrequiring phenylalanine hydroxylase.phenylalanine hydroxylase.

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