PROCESSING AND ANALYSIS OF METHAPHASE AND CHROMOSOMEIMAGES
Institute of Mathematics and Informatics, Bulgarian Academy of Sciences, Acad. G. Bonchev St., bl. 8, 1113 Sofia, Bulgaria E-mail: email@example.com
The paper describes the realization of procedures for processing andanalysis of metaphase and chromosome images. Image processing procedures include preprocessing and image segmentation. Analyzing procedures extract methaphase and chromosome features. Adescription of these procedures and corresponding data structures isgiven.
Chromosome analysis intelligent system (CAIS) is developed to perform chromosomeanalysis and classification. Methaphase and chromosome image processing and analysisare based on analyzing the gray-level images of biological objects on a microscope slide.The images are composed of biological objects nearly well spread and distinguishablefrom the background. Image processing methods include preprocessing and imagesegmentation. Analysis methods extract methaphase and chromosome features to form asymbolic image description. All these methods are applied on large data structures like pixel arrays. A high efficiency and a lower degree of flexibility are required to handlesuch large amounts of data. To be successfully realized these methods should beimplemented as appropriate efficient procedures. This problem requires special domain-oriented knowledge about image processing and chromosome classification. The present paper describes the realization of metaphase and chromosome image processing andanalysis procedures organized in classes of objects [1,2].
2.Image processing procedures
This section contains a short description of procedures for methaphase and chromosomeimage processing.
2.1Loading an image from a file
The system is working on 256-grey-level images in the following graphic file formats: