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linicians are sometimessurprised when they re-fer an animal with a der-matologic problem to a specialistwho rapidly compiles a list of dif-ferential diagnoses and pinpointsspecific tests to be performed.There is nothing magical aboutthe dermatologist’s action! Al-though dermatologists routinelysee various cutaneous lesions, itis their ability to properly identifythese lesions that provides thecritical information necessary tocompile a list of diagnostic differ-entials and select appropriatetesting.Key to making a diagnosisand treating a previously unseendermatologic problem is keep-ing an open mind to the possi-bility of a novel diagnosis andstarting with the usual historytaking. After a very thoroughhistory, the basic morphologyof cutaneous lesions must bereviewed. Then, the predomi-nant pattern of lesions shouldbe determined and the same al-gorithmic approach used forany other problem followed.To make a correct dermato-logic diagnosis, clinicians mustfirst be able to recognize prima-ry and secondary lesions andbe able to associate them with apredominant morphologic pat-tern. This column focuses onthe evidence that clinicians can
see 
during a clinical examina-tion; this evidence is coupledwith the patient history to nar-row the diagnostic possibilities.Although seemingly easy,correctly describing a skin con-dition can be quite difficult. Todo pattern diagnosis effectively,descriptions must be preciseand accurate. Differentiating ascale from crust or a papulefrom a plaque, for example, iscritical. Without a correct de-scription of the morphologicpattern, accurate diagnosis isusually impossible. Table Oneprovides an easy-to-use list oflesions, their descriptions, andthe morphologic pattern associ-ated with each. In summary,approaching each case in threedistinct steps will allow the clin-ician to make a correct diagno-sis in most cases (see the box).
Determine Pattern
Using your knowledge of pri-mary and secondary lesions,carefully evaluate the animal todetermine the predominantpat-tern. This is done by asking a se-ries of questions in a specific or-der (see the algorithm). Alwaysselect the predominant pattern. Adog with profound scaling andthree pustules does not have avesiculopustular disorder; it has
The Compendium 
September 1996Small Animal
tables provided here (Tables Twothrough Nine). Making such a listnot only increases your aware-ness of possible dermatologicconditions but provides an ex-tremely helpful reference thatcan accompany samples submit-ted for diagnostic testing (espe-cially biopsies for histopathologicassessment).
Perform DiagnosticTesting 
With a pattern diagnosis anddifferential diagnostic list, thepossible diagnoses can be nar-rowed. With experience, it is
The Pattern Approach toDermatologic Diagnosis
PERSPECTIVES IN VETERINARY MEDICINE
Lowell Ackerman, DVM, PhDDiplomate, ACVDDermvet Inc.Scottsdale, Arizona
an exfoliative dermatosis. A catwith a large, hairless mass on itsback has a papulonodular der-matosis, not alopecia. There areeight major categories of pre-dominant patterns.
Formulate DifferentialDiagnostic List 
Once you have determined thefit between your case and one ofthe eight major categories, youcan create a comprehensive dif-ferential diagnostic list from thepossible to prioritize the mostlikely diagnoses and performtests accordingly. At first, how-ever, information in Table Tencan be used to create a mini-mum data base, which will revealthe most common condition as-sociated with a particular presen-tation. If the minimum data basedoes not suggest a diagnosis,proceed to the
next step
col-umn in Table Ten. By followingthis approach, a diagnosis canbe made in most cases.
s
Most dermatologic problems have a characteris-tic clinical presentation.
s
 A differential diagnostic list can often be madeby assigning clinical cases into one of eightmajor categories of predominant lesion patterns.
s
Deciding which diagnostic tests to performbecomes more routine if the lesions have beengrouped into one of the eight major categories.
    K    E    Y    P    O    I    N    T    S
V
How To Make a CorrectDermatologic Diagnosis
Step 1
Determine pattern.
Step 2
Formulate differential diagnostic list.
Step 3
Perform diagnostic testing.
 
Small Animal
The Compendium 
September 1996
    K   e   y   D   e   s   c   r    i   p   t    i   o   n   o    f    l   e   s    i   o   n   s    P   r   e    d   o   m    i   n   a   n   t    l   e   s    i   o   n   p   a   t   t   e   r   n   s
    I   n    i   t    i   a    l    A    l   g   o   r    i   t    h   m
   n   o   n   o   n   o   n   o   n   o   n   o   n   o   n   o   y   e   s   y   e   s   y   e   s   y   e   s   y   e   s   y   e   s   y   e   s   y   e   s   y   e   s   n   o    P   r    i   m   a   r   y   p    i   g   m   e   n   t   a   r   y   c    h   a   n   g   e   s    ?    R   a    i   s   e    d    l   e   s    i   o   n   s    ?    F    l   a   t ,    d   e   p   r   e   s   s   e    d ,   o   r   m    i    l    d    l   y   e    l   e   v   a   t   e    d    l   e   s    i   o   n   s    ?    F    l   u    i    d  -    f    i    l    l   e    d    l   e   s    i   o   n   s    ?    S   o    l    i    d   a   n    d   r   a    i   s   e    d    l   e   s    i   o   n   s    ?
 
    H   a    i   r    l   o   s   s   p   r   o   m    i   n   e   n   t    ?    R   e   e   v   a    l   u   a   t   e   p   a   t   t   e   r   n    R   e   e   v   a    l   u   a   t   e   p   a   t   t   e   r   n    B   r   e   a    k   s    i   n   e   p    i   t    h   e    l    i   a    l    i   n   t   e   g   r    i   t   y    ?    S   c   a    l    i   n   g   p   r   o   m    i   n   e   n   t    ?    S    k    i   n   t    h    i   c    k   e   n   e    d    ?    P    i   g   m   e   n   t   e    d    l   e   s    i   o   n   s   a   n    d    d   e   r   m   a   t   o   s   e   s    V   e   s    i   c   u    l   o   p   u   s   t   u    l   a   r    d   e   r   m   a   t   o   s   e   s    P   a   p   u    l   o   n   o    d   u    l   a   r    d   e   r   m   a   t   o   s   e   s    A    l   o   p   e   c    i   c    d   e   r   m   a   t   o   s   e   s    E   r   o   s    i   v   e  -   u    l   c   e   r   a   t    i   v   e    d   e   r   m   a   t   o   s   e   s    E   x    f   o    l    i   a   t    i   v   e    d   e   r   m   a   t   o   s   e   s    I   n    d   u   r   a   t   e    d    d   e   r   m   a   t   o   s   e   s    M   a   c   u    l   o   p   a   p   u    l   a   r    d   e   r   m   a   t   o   s   e   s
 
The Compendium 
September 1996Small Animal
TABLEONE
Pattern Diagnosis
Lesion Description Pattern Associatio
MaculeA circumscribed, flat discoloration of the skin up to1 cm in diameterMaculopapularPigmentedPatchMacules >1 cmMaculopapularPigmentedPapuleA circumscribed, elevated, superficial, solid lesionup to 1 cm in diameterMaculopapularPlaqueA circumscribed, elevated, superficial, solid lesion>1 cm; a papule that has enlarged in two dimensionsPapulonodular (plaque) WhealAn edematous, transitory papule or plaquePapulonodular (plaque)Indurated (turgid)NoduleA solid lesion with depth; a papule that has enlargedin three dimensionsPapulonodular (nodule)VesicleA circumscribed elevation of the skin up to 1 cm indiameter and containing serous fluidVesiculopustularBullaA vesicle >1 cm in diameterVesiculopustularPustuleA circumscribed elevation of the skin containingpurulent fluidVesiculopustularEpidermal collaretteA circular peeling rim of scaleVesiculopustularPetechiaA circumscribed deposit of blood or blood pigmentup to 1 cm in diameterPigmented (red)PurpuraA circumscribed deposit of blood or blood pigment>1 cm in diameterPigmented (red)CrustVariously colored collections of skin exudatesErosive-ulcerativeExcoriationAbrasion of the skin, usually superficial andtraumatic in originMaculopapularFissureA linear break in the skin that is sharply defined with abrupt wallsMaculopapularPapulonodularExfoliativeErosionAn excavation in the skin limited to the epidermisand not breaking the integrity of thedermoepidermal junctionErosive-ulcerativeUlcerAn irregularly sized and shaped cavitation in theskin extending into the dermisErosive-ulcerativeScarA formation of connective tissue replacing tissuelost through injury or diseaseInduratedLichenificationA diffuse area of thickening and scaling, withresultant increase in the skin lines and markingsMaculopapularInduratedExfoliativeScaleShedding dead epidermal cells that may be dry orgreasy ExfoliativeMaculopapularIndurationPalpable thickening of the skinInduratedSclerosisHardening of the skinInduratedHyperpigmentationDarkening of the skinPigmented (dark)Maculopapular
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