Welcome to Scribd. Sign in or start your free trial to enjoy unlimited e-books, audiobooks & documents.Find out more
Standard view
Full view
of .
Look up keyword
Like this
0 of .
Results for:
No results containing your search query
P. 1
Granulomatous Lesions of Nose

Granulomatous Lesions of Nose

|Views: 3,177|Likes:
This E book discusses the various granulomatous lesions involving the nose and its management.
This E book discusses the various granulomatous lesions involving the nose and its management.

More info:

Published by: Dr. T. Balasubramanian on Dec 07, 2009
Copyright:Attribution Non-commercial


Read on Scribd mobile: iPhone, iPad and Android.
download as PDF, TXT or read online from Scribd
See more
See less





Granulomatous lesions of nose and paranasal sinuses
ByDr. T. Balasubramanian M.S. D.L.O.www.drtbalu.co.in
 Definition:Many chronic inflammations involving the nose and paranasal sinuses are characterized by formation of granulation tissue infiltrated by chronic inflammatory cells. These lesionsalso are known as granulomata. Majority of these granulomata are caused by specificinfectious organism and hence known as "Specific granulomata". While in others, theetiology is not clearly evident and is hence known as "Non specific granulomata" or morecommonly “Midline non healing granulomata". Diagnosis of these lesions is only possible by histological examination / microbiological examination of the lesion.Histologically, the principal components of any granulomatous lesion are considered to be macrophages, epithelioid cells and multinucleated giant cells. Necrosis and vasculitiscould also be seen in varying degrees. The role of previous therapy should also beconsidered as they could very well have modified the lesions.*Caution: Many of granulomatous lesions of nose and PNS do not show these features.Classification of Nasal granulomas:Specific:1. Tuberculosis2. Leprosy3. Syphilis4. Yaws5. Scleroma6. Actinomycosis7. Aspergillosis8. Mucormycosis9. Rhinosporidiosis10. Leishmaniasiswww.drtbalu.co.in
 11. AIDS Nonspecific:1. Sarcoidosis2. Wegner's granulomatosis3. Sinonasal lymphoma4. Eosinophilic granulomaTuberculosis:Tuberculous lesions involving nasal mucosa is very rare. It is always associated with primary pulmonary tuberculosis.Macroscopic appearance:1. Ulcers2. Polypoidal lesions3. Nodular lesionsUlcers are commonly found on the anterior part of the nasal septum, inferior turbinateand anterior choanae.Lupus vulgaris:This is an indolent and chronic from of tuberculous infection affecting the skin andmucous membrane of nose. It is two times more common in women than in men... It isknown to affect young adults. It is infact a disease of temperate climate and is rare intropics.The mucocutaneous junction of the nasal septum is the most common location of theselesions. This could also very well be the site of inoculation, as it is more exposed totrauma in patients with the habit of nose picking. Nasal lesions are frequently associatedwith or could be considered to be precursor to nodules on the face.Histopathology:Sections of these lesions show the classic features of tuberculous granuloma. In thecentre these lesions show collection of reticuloendothelial cells. These cells soon necrosewww.drtbalu.co.in

Activity (9)

You've already reviewed this. Edit your review.
1 hundred reads
1 thousand reads
Mostafa Kamel Temraz liked this
Niveditha Gowda liked this
dr_udaykiran liked this
pkafle liked this
Selvin Jayanth liked this
Abouzr Mohamed Eshag liked this
Meesha Sunti liked this

You're Reading a Free Preview

/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->