Ophiorrhiza rugosa var. prostrata
(Mongoose plant, Indian snakeroot,
containing camptothecin (CPT), an alkaloid used in the treatment of cancer & has been found comparable to the CPT in 'Mappia foetida', a tree known for its anti-cancer properties.
Cancer chemo-preventive potential of Luteolin-7-O-Glucoside isolated from
are genera of Rubiaceae. Some biological activities of some isolated compounds and extracts of both genera. Ethnomedicinal and phytochemistry uses include the treatment of malaria, diarrheal and other digestive problems, skin diseases, fever, hemorrhage, urinary and respiratory infections, headache, inflammation of eye, and gums. To date, more than 60 compounds have been reported from
species including alkaloids, iridoids, flavonoids, terpenoids, and other compounds. Studies have confirmed that extracts from
species as well as their isolated compounds possess diverse biological activities, including anti-inflammatory, antitumor, antimicrobial, larvicidal, antioxidant, gastrointestinal, anti-ulcer, and hepatoprotective, with alkaloids and iridoids as the major active principles.
The bark of trees in the genus
is the source of a variety of alkaloids, the most familiar of
which is quinine, one of the first agents effective in treating malaria. Woodruff (
) is a small herbaceous perennial that contains coumarin
and the South American plant