Understanding Cancer and Related Topics

Understanding Estrogen Receptors,

Tamoxifen, and Raloxifene
These PowerPoint slides are not locked files. You can mix and match slides from different tutorials as
you prepare your own lectures. In the Notes section, you will find explanations of the graphics.
The art in this tutorial is copyrighted and may not be reused for commercial gain.
Please do not remove the NCI logo or the copyright mark from any slide.
These tutorials may be copied only if they are distributed free of charge for educational purposes.
Developed by:
Lewis J. Kleinsmith, Ph.D.
Donna Kerrigan, M.S.
Jeanne Kelly
Describes the hormone estrogen and its
receptor. Explains the relationship of estrogen
and its receptor to breast cancer and the risks
and benefits of reducing cancer risk with drugs
called antiestrogens and selective estrogen
receptor molecules (SERMs).
!"#$ &'( )*$'+,(-*.
)*$'+,(- /#',($* /0**1(*
)*$'+,(- 2(3(4$+'*
)*$'+,(- 2(3(4$+'*
/'0,,(' 5(-( &367#6+-
)*$'+,(-89-:13(:
;"#-,(* 0- ;(<< =("#70+'
)*$'+,(-89-:13(:
>6?1<#6+- +@ ;(<< A'+<0@('#6+-
)*$'+,(- #-: ;#-3('
)*$'+,(- #-: ='(#*$ ;#-3('
;#-3(' &'0*(* B'+?
CD& E1$#6+-* 0- ;(<<*
)*$'+,(-89-:13(: A'+<0@('#6+-
+@ )F0*6-, E1$#-$ ;(<<*
)*$'+,(-89-:13(: A'+<0@('#6+- #-:
>4+-$#-(+1* D(G E1$#6+-*
)*$'+,(- #-: H$('0-( ;#-3('
&-6(*$'+,(-*
>)2E*
/#?+F0@(- #-: ;#-3('
Tamoxifen and Breast Cancer Treatment
&'+?#$#*( 9-"0I0$+'*
)*$'+,(- 2(3(4$+'8D(,#67(
='(#*$ ;#-3('
Tamoxifen and Breast Cancer Prevention
/#?+F0@(- #* # ;#1*( +@ H$('0-( ;#-3('
/"( D((: @+' =(J(' >)2E*
)*$'+,(- 2(4<#3(?(-$ 0- E(-+4#1*(
)*$'+,(- A<1* A'+,(*6- 2(4<#3(?(-$
>(#'3" @+' $"( A('@(3$ >)2E
2#<+F0@(-( #-: $"(
A'(7(-6+- +@ K*$(+4+'+*0*
2#<+F0@(-( #-:
20*L +@ 9-7#*07( ='(#*$ ;#-3('
We would like to hear from you . . .
If you have questions about this tutorials content, suggestions for new topics, or
other feedback on the Web site, please send an e-mail to kerrigad@mail.nih.gov.
If you have questions about this tutorials artwork or want permission to use it,
please send an e-mail to beankelly@verizon.net.