Welcome to Scribd, the world's digital library. Read, publish, and share books and documents. See more
Download
Standard view
Full view
of .
Look up keyword
Like this
3Activity
0 of .
Results for:
No results containing your search query
P. 1
Pharmacody Namics

Pharmacody Namics

Ratings: (0)|Views: 133|Likes:
Published by chocoholic potchi

More info:

Published by: chocoholic potchi on Dec 17, 2009
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PPT, PDF, TXT or read online from Scribd
See more
See less

05/16/2011

pdf

text

original

 
 
Pharmacodynamics
Ma. Minda Luz M. Manuguid,M.D.
 
 
Pharmacodynamics
Pharmacodynamics– deals with theaction of a drug on the body; what thedrug does to the body;
Mechanisms of Drug Actionon thebory:
Receptor interactions
Dose-related phenomena
 Therapeutic action
 Toxic effects
 
 
Definitions
Agonist– drug that triggers the same events as thenative ligand when it binds to a receptor
Antagonist– drug that prevents binding of the nativeligand to the receptor so that it sannot produce itsnormal action
Affinity– ability of a drug to bind to a receptor (howwell a drug & a receptor recognize each other)
Potency– quantity of a drug needed to achieve adesired effect; more potent, lower EC50
Quality
 – bioavailability of the drug
Efficacy– maximal effect an Agonist can achieve atthe highest practical concentration ( a measure of how well a drug produces a response); high Emax

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->