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Bioinformatics Syllabus for M.Sc.

Bioinformatics Syllabus for M.Sc.

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CURRICULUM FOR M.Sc. IN BIOINFORMATICS
SESSION 2005-2007Brijesh Singh Yadav(brijeshbioinfo@gmail.com)
Paper CodeNomenclature of paperMax/(Min)MarksTotal(Th./Prac.)Int. / Sess.M.Sc. (Bioinformatics) First Semester
MBI-101 (B)*Basic Mathematics80(29)20(10)100MBI-102 (T)Introduction to Bioinformatics80(29)20(10)100MBI-103 (T)Introduction to Concept in Computing & Computer Programming80(29)20(10)100MBI-104 (T)Internet Technology & Distributed Computing80(29)20(10)100MBI-105 (T)Cell Biology & Genetics80(29)20(10)100MBI-106 (P)S/W Lab I Problems based on MBI-10380(40)20(10)100MBI-107 (P)S/W Lab II Problems based on MBI-10480(40)20(10)100
M.Sc. (Bioinformatics) Second Semester
MBI-201 (T)Biological Database, Data Mining & Data SecurityTechniques80(29)20(10)100MBI-202 (T)Introduction to Database System80(29)20(10)100MBI-203 (T)Programming in Object Oriented Languages80(29)20(10)100MBI-204 (T)Pharmacology & Chemoinformatics80(29)20(10)100MBI-205 (T)Structural Biology 80(29)20(10)100MBI-206 (P)S/W Lab III Problems based on MBI-20280(40)20(10)100MBI-207 (P)S/W Lab IV Problems based on MBI-20380(40)20(10)100MBI-208 (MP)Minor Project80(40)20(10)100
M.Sc. (Bioinformatics) Third Semester
MBI-301 (T)Computer Graphics & Visualization80(29)20(10)100MBI-302 (T)Machine Learning Techniques (Advanced Computing)80(29)20(10)100MBI-303 (T)Genome to Drug & Vaccine80(29)20(10)100MBI-304 (T)Metabolomes & Metabolic Pathway80(29)20(10)100MBI-305 (T)Emerging Areas in Bioinformatics80(29)20(10)100MBI-306 (P)S/W Lab V Problems based on MBI-30180(40)20(10)100MBI-307 (P)S/W Lab VI Problems based on MBI-30280(40)20(10)100
M.Sc. (Bioinformatics) Fourth Semester
MBI-401 (T+P)Seminars on Applications of Bioinformatics inAgriculture/ Human Health/ Environment/ Biotechnology/Molecular Biology/ Neurobiology/ Drug Designing/Veterinary Sciences100(50)100(50)200MBI-402 (PP)Research Paper Presentation100(50)100(50)200MBI-403 (PR)Major Project200(100)200(100)400
Grand Total of Marks = 3000
* Students from mathematics/ Computer Stream will study paper MBI-101(A)* of Basic Biology,whereas students from biology/ agriculture stream will study paper MBI-101(B)* of BasicMathematics.
 
Department of Computer Science, A.P.S. University, Rewa (M.P.)
Syllabus for M.Sc. Bioinformatics - First Semester
(Session 2004-2006)
PAPER (MBI-101(B)) BASIC MATHEMATICS.Max.Marks. 80Time: 3 hours Min.Marks. 29 
Unit I
Calculus
: Limits, Complete Differentials, Partial differentials of functions withone variable and multiple variables.
Integration
: Elementary Integration, Definite and Non-definite integral; Series,Logarithms.
Differential Equation
: Ordinary differential equations (first order), Partialdifferential equations.
Unit II
Vector 
: Addition, subtraction, dot, cross, scalar triple product, divergence, curl of a vector, equation of normal
Matrix algebra
: Addition, subtraction, multiplication, transpose inverse, andconjugate of matrix etc.
Trigonometric functions
: Sin, Cos, Tan, Cot, Series expansion of these functionsand other related functions
Unit III
Correlation, Covariance, Calculation of covariance
Correlation analysis, Types of correlation, Scatter Diagram
Regression analysis, Regression coefficients
Probability Terms and concepts
Definition, Simple problems involving probability
Unit IV
Introduction to Biostatistics
Measures of central tendency, Mean, Median, Mode, Mean Deviation, StandardDeviation
Chi-Square Test, Degrees Of Freedom, Chi-Square Distribution, Properties of Chi-Distribution
References:
P.N. Arora,P.K. Malhan ,Biostatistics ,Himalaya Pub.
Mohan.P. Arora,Fundamentals Of Genetics,Himalaya Pub
P.N.Arora : Fundamentals Of trigonometry and Matrix
Manjeet Singh: Simple approach to calculus
Note: In all there will be NINE questions. Two questions are to be asked from each of the four units (with internal choice ineach unit). The students are expected to attempt only one question from each unit. The ninth question will consist of fourshort notes (one from each unit), out of which only two are to be attempted.
 
Department of Computer Science, A.P.S. University, Rewa (M.P.)
Syllabus for M.Sc. Bioinformatics - First Semester
(Session 2004-2006)
PAPER (MBI - 102 (T) INTRODUCTION TO BIOINFORMATICSMax.Marks. 80Time: 3 hours Min.Marks. 29
Unit I
INTRODUCTION
Overview of bioinformatics
Resources
Genome projects
Pattern recognition and prediction
Unit II
DATABASES AND DATA RETRIEVAL
DNA Sequence Databases (GenBank, EMBL)
Protein Sequence Databases (SWISS-PROT, PROSITE)
Data/Sequence Retrieval From Databases
Genome Databases - Searching And Data Retrieval
Unit III
SIMILARITY/HOMOLOGY SEARCHING
Sequence Comparison/Homology searchers
BLAST
How BLAST Works
PSI-BLAST
BLASTing Against Specific Genomes
FASTA
Working of FASTA
Unit IV
SEQUENCE ANALYSIS
Sequence Alignment
Global and Local Alignment
Pair wise and Multiple sequence alignment
PAM and BLOSUM
CLUSTALW
Molecular phylogeny
Making tree
DNA/PROTEIN SEQUENCE ANALYSIS AND MANIPULATION
Open Reading Frame (ORF) Identification
Promoter Prediction And Analysis
DNA Restriction Analysis
DNA Sequence Translation To Amino Acid Sequence
Codon Usage analysis
General Programs Of Interest
Reference:
Attwood, T.K. and Parry-Smith, D. J. Introduction to Bioinformatics, Longmans
S. Sundara Rajan, R. Balaji, Introduction to Bioinformatics, Himalaya Pub.
 Note: In all there will be NINE questions. Two questions are to be asked from each of the four units (withinternal choice in each unit). The students are expected to attempt only one question from each unit. Theninth question will consist of four short notes (one from each unit), out of which only two are to beattempted.

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