Denise C. Park
BBS, Center for BrainHealth
972-883-3255
denise@utdallas.edu

CONTENT. This is a discussion-based seminar that will be focused on readings in the
cognitive neuroscience of aging. We will begin with an overview of cognitive aging
findings, integrate this with theoretical views of neurocognitive aging, and then consider
specific topics in the cognitive neuroscience of aging with an emphasis on memory,
individual differences, and normal aging.

CLASS FORMAT. The class will be discussion-based. We will review four articles per
week. Each member of the class will turn in two questions about the article. One person
will present a 15-minute summary of the article, along with a series of questions for the
class to discuss. This individual will also prepare a written outline of the article which we
will compile into a document for the entire class. This is the only written product for
individuals taking the class for two credits. Attendance and completion of readings are
required.

In addition to your presentations, you are required to prepare a research proposal on some aspect of the cognitive neuroscience of aging that is approximately 10 pages in length.

Note: This page can only be accessed when connected to the UTD network. In order to access course
materials when off campus, you will have to download and install the VPN client that UTD has made freely
available.

Davis, S. W., Dennis, N. A., Daselaar, S. M., Fleck, M. S., & Cabeza, R. (2008). Que PASA? The
posterior-anterior shift in aging. Cerebral Cortex (New York, N.Y.: 1991), 18(5), 1201-9. doi:
10.1093/cercor/bhm155.

Annual Review of Psychology, 60, 173-96. doi: 10.1146/annurev.psych.59.103006.093656.
Poldrack, R. A. (2008). The role of fMRI in cognitive neuroscience: where do we stand? Current Opinion
in Neurobiology, 18(2), 223-7. doi: 10.1016/j.conb.2008.07.006.
Reuter-Lorenz, P. A., & Cappell, K. A. (2008). Neurocognitive Aging and the Compensation Hypothesis.
Current Directions in Psychological Science, 17(3), 177-182. doi: 10.1111/j.1467-8721.2008.00570.x.
Stevens, W. D., Hasher, L., Chiew, K. S., & Grady, C. L. (2008). A neural mechanism underlying
memory failure in older adults. The Journal of Neuroscience: The Official Journal of the Society for
Neuroscience, 28(48), 12820-4. doi: 10.1523/JNEUROSCI.2622-08.2008.

Kaufmann, L., Ischebeck, A., Weiss, E., Koppelstaetter, F., Siedentopf, C., Vogel, S. E., et al. (2008). An
fMRI study of the numerical Stroop task in individuals with and without minimal cognitive impairment.
Cortex; a Journal Devoted to the Study of the Nervous System and Behavior, 44(9), 1248-55. doi:
10.1016/j.cortex.2007.11.009.
Pagnoni, G., & Cekic, M. (2007). Age effects on gray matter volume and attentional performance in Zen
meditation. Neurobiology of Aging, 28(10), 1623-7. doi: 10.1016/j.neurobiolaging.2007.06.008.
Velanova, K., Lustig, C., Jacoby, L. L., & Buckner, R. L. (2007). Evidence for frontally mediated
controlled processing differences in older adults. Cerebral Cortex (New York, N.Y.: 1991), 17(5), 1033-
46. doi: 10.1093/cercor/bhl013.
Waiter, G. D., Fox, H. C., Murray, A. D., Starr, J. M., Staff, R. T., Bourne, V. J., et al. (2008). Is retaining
the youthful functional anatomy underlying speed of information processing a signature of successful
cognitive ageing? An event-related fMRI study of inspection time performance. NeuroImage, 41(2),
581-95. doi: 10.1016/j.neuroimage.2008.02.045.
Zysset, S., Schroeter, M. L., Neumann, J., & Yves von Cramon, D. (2006). Stroop interference,
hemodynamic response and aging: An event-related fMRI study. Neurobiology of Aging. doi:
10.1016/j.neurobiolaging.2006.05.008.

Cook, I. A., Bookheimer, S. Y., Mickes, L., Leuchter, A. F., & Kumar, A. (2007). Aging and brain
activation with working memory tasks: an fMRI study of connectivity. International Journal of Geriatric
Psychiatry, 22(4), 332-42. doi: 10.1002/gps.1678.

Grady, C. L., Yu, H., & Alain, C. (2008). Age-related differences in brain activity underlying working memory for spatial and nonspatial auditory information. Cerebral Cortex (New York, N.Y.: 1991), 18(1), 189-99. doi: 10.1093/cercor/bhm045.

Hazlett, E. A., Byne, W., Brickman, A. M., Mitsis, E. M., Newmark, R., Haznedar, M. M., et al. (2008).
Effects of sex and normal aging on regional brain activation during verbal memory performance.
Neurobiology of Aging. doi: 10.1016/j.neurobiolaging.2008.10.005.

Brassen, S., B\u00fcchel, C., Weber-Fahr, W., Lehmbeck, J. T., Sommer, T., & Braus, D. F. (2007).
Structure-function interactions of correct retrieval in healthy elderly women. Neurobiology of Aging.
doi: 10.1016/j.neurobiolaging.2007.10.005.

Duarte, A., Graham, K. S., & Henson, R. N. (2008). Age-related changes in neural activity associated
with familiarity, recollection and false recognition. Neurobiology of Aging. doi:
10.1016/j.neurobiolaging.2008.09.014.

Duverne, S., Motamedinia, S., & Rugg, M. D. (2008). The Relationship between Aging, Performance,
and the Neural Correlates of Successful Memory Encoding. Cereb. Cortex, bhn122. doi:
10.1093/cercor/bhn122.

Trivedi, M. A., Schmitz, T. W., Ries, M. L., Hess, T. M., Fitzgerald, M. E., Atwood, C. S., et al. (2008).
fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors
for Alzheimer's disease. Neuropsychologia, 46(6), 1667-78. doi:
10.1016/j.neuropsychologia.2007.11.035.

10.1016/j.neurobiolaging.2006.12.017.
Dennis, N. A., Daselaar, S., & Cabeza, R. (2007). Effects of aging on transient and sustained successful
memory encoding activity. Neurobiology of Aging, 28(11), 1749-58. doi:
10.1016/j.neurobiolaging.2006.07.006.
Miller, S. L., Celone, K., DePeau, K., Diamond, E., Dickerson, B. C., Rentz, D., et al. (2008). Age-related
memory impairment associated with loss of parietal deactivation but preserved hippocampal
activation. Proceedings of the National Academy of Sciences of the United States of America, 105(6),
2181-6. doi: 10.1073/pnas.0706818105.
Viard, A., Piolino, P., Desgranges, B., Ch\u00e9telat, G., Lebreton, K., Landeau, B., et al. (2007).
Hippocampal activation for autobiographical memories over the entire lifetime in healthy aged
subjects: an fMRI study. Cerebral Cortex (New York, N.Y.: 1991), 17(10), 2453-67. doi:
10.1093/cercor/bhl153.
Wilson, I. A., Gallagher, M., Eichenbaum, H., & Tanila, H. (2006). Neurocognitive aging: prior memories
hinder new hippocampal encoding. Trends in Neurosciences, 29(12), 662-70. doi:
10.1016/j.tins.2006.10.002.

Riis, J. L., Chong, H., Ryan, K. K., Wolk, D. A., Rentz, D. M., Holcomb, P. J., et al. (2008).
Compensatory neural activity distinguishes different patterns of normal cognitive aging. NeuroImage,
39(1), 441-54. doi: 10.1016/j.neuroimage.2007.08.034.

Andrews-Hanna, J. R., Snyder, A. Z., Vincent, J. L., Lustig, C., Head, D., Raichle, M. E., et al. (2007).
Disruption of large-scale brain systems in advanced aging. Neuron, 56(5), 924-35. doi:
10.1016/j.neuron.2007.10.038.

Damoiseaux, J. S., Beckmann, C. F., Arigita, E. J. S., Barkhof, F., Scheltens, P., Stam, C. J., et al.
(2008). Reduced resting-state brain activity in the "default network" in normal aging. Cerebral Cortex
(New York, N.Y.: 1991), 18(8), 1856-64. doi: 10.1093/cercor/bhm207.