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NutriSearchComparativeGuide
to
NutritionalSupplements
Figure11-1
EighteenImportantHealthSupportCriteria
Completeness:looks
to
see
if
theproductcontainsalltheBlendedStandardnutrients.
AntioxidantSupport:
examinesthenutrients
that
help
to
prevent
or
repaircellulardamagecausedbyoxidation,includingvitamin
C,
vitamin
E,
vitamin
A,
beta-carotene,alpha-lipoicacid,Iycopene,coenzyme
Ql
0,
andselenium.
Lipotropic
Factors:examinesthosenutrients,includingcholine,lecithin,andinositol,
that
helpremovetoxins,includingheavymetalslikelead.Theliverandthebrainare
two
primarytargetsfortheaccumulation
of
fat-solubletoxins.
LiverHealth:
examinesthosenutrients(includingvitamin
C,
cysteineandn-acetyl-cysteine,selenium,vitamin
B2,
andvitamin
B3)
that
enhanceliverfunctionandoptimizelevels
of
glutathione,whichhelpscells
fight
off
toxicchallenges.
Metabolic
Health:
examinesthosenutrients
that
helpthe
body
handleitsdailysugarload,keepingsystemsresponsive
to
insulinandrestoringlostinsulinsensitivity.Thesenutrientsincludevitamin
B3
,vitamin
B6,
vitaminBl
2,
vitamin
C,
vitaminE,biotin,coenzyme
Q1
0,
chromium,magnesium,manganese,andzinc.
Potential
Toxicities:examinesthosenutrients
that
canbuild
up
inthebody,
-----Ur:
possiblyleading
to
toxiclevels
with
long-termintake.ThisincludesvitaminAandiron.Accidentaloverdose
of
iron-containingsupplements
is,
infact,aleadingcause
of
fatalpoisoninginchildren.VitaminA
is
available,safely,
as
beta-carotene,whileadequateiron
is
easilyobtainableformostpeoplefromfoods.
Mineral
Forms:examinesthemolecules
that
mineralsarebound
withto
helpthemcrossintothebloodstream.Aminoacidchelatesandorganicacidcomplexes(such
as
citratesandgluconates)mimicthenaturalmineralchelates
that
formduringthedigestiveprocess.Chelatedmineralsalsoappear
not
to
blockothermineralsfrombeingabsorbed,unlikemany
of
the
less
expensivemineralsalts(carbonates,sulphates,andchlorides).BoneHealth:examinesthenutrients
that
assistinboneremodeling,vital
to
ward
off
osteoporosisandother
diseases
thatweakentheskeletalframework.Thesenutrientsincludevitamin
D,
vitamin
K,
vitamin
C.
vitamin
B6,
vitaminBl
2,
folicacid,boron,calcium,magnesium,silicon,andzinc.
PhenolicCompounds
Profile:examinesaspecific
group
of
phenoliccompounds(polyphenolicacidsand
their
derivatives),known
to
beexceptionally
potent
defendersagainstfreeradicals.Phenolsderivedfromolives,greentea,andcurcuminarealsoknown
to
improve
major
riskfactorsforcardiovasculardisease,including
lowering
theimpact
of
inflammation.
Page
80
Potency:looks
to
see
how
much
of
eachnutrientthe
product
containscompared
to
theBlendedStandardamounts.
Bioactivity
of
Vitamin
E:
looks
to
see
if
thevitaminE
is
thenatural
or
syntheticform.Naturalformsincluded-alphatocopherol,whilesyntheticvitamin
E,
only
half
as
effective,
is
usuallyintheform
of
d,l-alphatocopherol.
OcularHealth:
Goodeyesightandprevention
of
cataractsandmaculardegenerationrequireadequatelevels
of
severalnutrients,includingvitamin
C,
vitamin
E,
vitaminA(includingbeta-carotene),andthecarotenoids,luteinandzeaxanthin.
GlycationControl:
examinesthosenutrients(I-carnosine,alpha-tocopherol,gamma-tocopherol,vitamin
C,
andalpha-lipoicacid)
that
helpslowtheprogress
of
manydegenerativediseases,includingParkinson'sdisease,Alzheimer'sdisease,andcancer.
Heart
Health:
examinesnutrients
that
helpprotecttheheartandcardiovascularsystem,includingvitamin
E,
beta-carotene,coenzyme
Q10,
calcium,magnesium,l-carnitine
or
acetyl-I-carnitine,procyanidolicoligomers(peOs),phenoliccompounds,andIycopene.
GammaTocopherol:
checks
to
see
if
the
product
includesthegammaformofvitamin
E.
Studiesshow
that
gamma
~ I : - - - - - t ~ ~ ; . . - - - - _
tocopherolreduceschronicinflammationandprotectsagainstcancers
of
thecolonandprostate.High-dosesupplementation
with
alphatocopherolalonecanreducethelevel
of
gammatocopherolin
body
tissues.
MethylationSupport:
looksatthosenutrients,includingvitamin
B2,
vitamin
B6,
vitaminB
12,
folic
acid,
andtrimethylglycine,requiredforthe
bodyto
producemethyldonormolecules.Methyldonorshelpreducehomocysteinelevelsintheblood,protectingthearteriesandnervefibres.
Inflammation
Control:
examinesthenutrientsresponsibleforreducinginflammationatthecellularlevel,such
as
omega-3
oils-including
thosefoundinfishoil(eicosapentaenoicanddocosahexaenoicacids,or
EPA
and
DHA)-linolenic
acid,gamma-tocopherol,alpha-lipoicacid,vitamin
C.
f1avonoids,procyanidolicoligomers,andthephenoliccompounds.Chronicinflammationcanlead
to
seriousdegenerativedisease,includingheartdisease,cancersandarthritis.
Bioflavonoid
Profile:
examinesthebioflavonoidfamily
of
nutrients,which
workthroughout
the
body
to
attackfreeradicalsandsupportmanybodilyfuctions.These
important
nutrientsincludecitrusf1avonoids,
soy
isoflavones,quercetin,quercitrin,hesperidin,rutin,bilberry,assortedberryextracts,and
PCOs
(includingresveratrol,grapeseed,andpinebarkextracts).
NutriSearchComparativeGuide
to
NutritionalSupplements
Qualitymeans
doing
itrightwhen
noone
islooking.
-Henry
Ford
(1863-1947)
CHAPTERTEN
MEDALS
OFACHIEVEMENT
How
theProgramWorks
Forthoseproductsreceivingafive-starrating
in
theinitialproductassessment,NutriSearchcontactseachmanufacturerandinvitesthemtoparticipate
in
the
NutriSearchMedal
of
AchievementProgram:·
Amanufacturermaythenchoosetoapplytoone
of
theabove-notedagenciesfora
GMP
audit
and/or
finishedproductanalysis.Thosemanufacturersdecidingnottoparticipate
in
the
NutriSearchMedal
of
AchievementProgram'·
forfeittheiropportunitytodemonstratesuperiorproductqualityandreceivenofurtherrecognitionbeyondtheirfive-starrating.Uponsuccessfulcompletion
of
GMP
and/or
productverification,themanufacturer
is
requitedto
submit
notarizeddocumentation
of
suchtoNutriSearch.
Once
thisdocumentationhasbeenreviewedandaccepted,NutriSearchwillensurethatthemanufacturer'sproduct
is
appropriatelydisplayed
in
the
All
manufacturerswhowish
to
receive
GOLD
Medalrecognition
MUST
submit
theirproduct{s)
to
acomprehensivelaboratoryanalysis
of
activeingredients,usingtheirchoice
of
one
of
thethreeabove-mentionedindependentprocedures.
Number(DIN),
acurrentCanadianNaturalProduct
Number(NPN),
oracurrentlisting
in
theAustralianRegister
of
TherapeuticGoods.
GOLD
medalstatusrequirestwoelements:
GMP
certificationandlaboratoryverification
of
theproduct'sformulation,includingidentityandpotency.ManufacturersthatqualifyforSILVERstatus(based
on
GMP
compliance)andthatprovidewrittendocumentation
of
thesuccessfulcompletion
of
arecognized,third-partylaboratoryanalysis
of
product
content
willreceiveaNutriSearch
GOLD
Medal
of
Achievement:·
Tomeetthestandard
of
evidence,NutriSearchwillacceptnotarizedcertificates
of
analysisfromeitherthe
NSF
InternationalDietarySupplementVerification
Program,
or
the
USPDietarySupplementVerification
Program.
NutriSearchwillalsorecognize
as
anacceptablestandard
of
evidenceanotarizedcertificate
of
analysisfromanindependentthird-partylaboratorythatmeetscurrentISO17025standards.Productsthatreach
five
starsareeligibletoparticipateinthe
NutriSearchMedal
of
AchievementProgram,'·
whichawards
GOLD,
SILVER,
or
BRONZE
medalsbasedonanassessment
of
thetype
of
Good
ManufacturingPractice(GMP)usedtomanufacturetheproduct,
and
onthird-partylaboratoryverification
of
theproduct'sformulation.Toreach
BRONZE
status,themanufacturermustdemonstratecompliancewithanationallyrecognizedcertificationprogramfor
GMP
based
on
afoodmodel.Manufacturersthathavecompletedandcan
document
acurrentandvalid
"A"
ratingfor
GMP
compliancewiththeNaturalProductsAssociation(NPA)[formerlytheNationalNutritionalFoodsAssociation(NNFA)]
GMP
CertificationProgramwillreceivetheNutriSearch
BRONZE
Medal
of
Achievemenc'·fortheselectedproduct.Tomeetthestandard
of
evidence,themanufacturermustsupplywrittendocumentation
of
boththesuccessfulcompletion
of
the
NPA
auditandcurrentgoodstandingwiththeNPAprogram.ToreachSILVERstatus,themanufacturermustdemonstratecompliancewithanationallyrecognizedcertificationprogramfornaturalhealthproduct
(NHP)-model
GMP
(Canada),medicinal
product-model
GMP
(Australia),
pharmaceutical-model
GMP
(US).Manufacturersthathavecompletedandcan
document
acurrentandvalid
audit
for
GMP
compliancewiththe
NSF
InternationalDietarySupplementVerificationProgram,
theUnitedStatesPharmacopoeia(USP)DietarySupplementVerificationProgram,CanadianNatural
Health
ProductsDirectorate
(NHPD)*
sitelicensing,orAustralianTherapeuticGoodsAdministration
(TGA)t
sitelicensingreceivetheNutriSearchSILVERMedal
of
Achievement'·fortheselectedproduct.Tomeetthestandard
of
evidence,NutriSearchwillacceptwrittendocumentation
of
thesuccessfulcompletion
of
theNSForUSPauditsandcurrentgoodstandingwitheitherprogram,acurrentCanadian
Drug
Identification
In
Canada,nutritionalsupplemcIHs-inciudingviramins,minerals,
and
herbal
productssold
in
dosage
form-are
classified
asnarural
heahhproducts
and
arc
federally
regulated
by
Health
Canada'saruralHeallh
Produc"
Direcrorate
(NHPD).
Theseproductsbeareithera
Drug
Idelllity
Number(DIN)or
aNaturalHealthProduct
Number
(P).Conversely,
in
the
United
Stares,
suchproducts
are
commonlyknown
as
dict,uy
supplemclHs
and
are
regulated
like
foods.
In
AusrraJia,
dierary
supplements
are
classified
as
Listed
Medicinal
Productsand
arc
regulated
under
theAustralian
ThcrapeuricGoodsAuthority.Theseproducts
bear
a
numerical
identifier
(Aust-L)andarelisted
in
theAustralianRegister
of
TherapeuticGoods.
Page
65
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