• Monitor patient for seizures. May occur within recommended dose range. Risk increased with higher doses and inpatients taking antidepressants (SSRIs, tricyclics, or Mao inhibitors), opioid analgesics, or other durgs that decrese the seizure threshold.• Overdose may cause respiratory depression and seizures. Naloxone (Narcan) mayreverse some, but not all, of the symptoms of overdose. Treatment should besymptomatic and supportive. Maintain adequate respiratory exchange.• Encourage patient to cough and breathe deeply every 2 hr to prevent atelactasis and pneumonia.
Histamine H2 antagonists
20 mgIV q8h
MECHANISM OF ACTION
• Inhibits the action of histamine at the H2 receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion.• In addition, ranitidine bismuth citrate has some antibacterial action against H. pylori.
•Treatment and prevention of heartburn, acid indigestion, and sour stomach.
Contraindicated in:•Hypersensitivity, Cross-sensitivity may occur; some oral liquids contain alcohol andshould be avoided in patients with known intolerance.Use Cautiously in: