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Urticaria (DRSAM)

Urticaria (DRSAM)

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Published by Dr. Momin Sohil

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Categories:Types, Research
Published by: Dr. Momin Sohil on Dec 28, 2009
Copyright:Attribution Non-commercial

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07/21/2013

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HYPERSENSITIVITY TYPE IImmediate responseAntibody mediated
Antigen in Sensitized individual
I/V or I/M injection – Systemic or Generalized ANAPHYLAXISeg.Anaphylactic Shock 
Injected or apply locally in skinLocal ANAPHYLAXISe.Urticaria , Rhinorrhoea
 
 
HYPERSENSITIVITY TYPE IImmediate responseAntibody mediated
Antigen given to Sensitized individual
Injected in passively sensitized personPassive cutaneous anaphylaxiseg. multiple skin sites
Encountered everyday life readilysensitized spontaneously-ATOPYeg.Hay fever, Asthma, Urticaria
 
 
Ag
Mucosal lining
IgE antibodies
Mast cellarming
Ag
Re-exposureSHOCKINGANTIGEN
AgAgAgRelease of MediatorsHistamineSerotonineVasoactive aminesDegranulationOf mast cellsSENSITIZATIONSkin –Nerve endings -Itching burningVasodilatation –- OedemaIncr. Capillary permeability - hyperaemia

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