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Sunbeds and Cancer

Sunbeds and Cancer

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Published by Alexander Wunsch
Reading list from Alexander Wunsch using "sun bed skin cancer" as search words.
Reading list from Alexander Wunsch using "sun bed skin cancer" as search words.

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Published by: Alexander Wunsch on Dec 28, 2009
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Sunbeds - CitaviSunbeds - CitaviSunbeds - CitaviSunbeds - Citavi Austin, A. S.; Spiller, R. C. (2001): Inflammatory bowel disease, azathioprine and skin cancer: case report andliterature review. In: Eur J Gastroenterol Hepatol, Jg. 13, H. 2, S. 193–194. AbstractA 42-year-old blond Caucasian woman taking azathioprine for 8 years developedan intra-epidermal carcinoma of the shin. She regularly used a sun bed to maintaina tan. Although the increased risk of non-melanoma skin cancer inimmunosuppressed transplant recipients is well recognized, patients with Crohn‘sdisease are not currently warned of the risk of exposure to ultraviolet light.Individuals with inflammatory bowel disease who take azathioprine, especially thosewith a fair complexion, should be informed of the potential dangers of sun bathingand should be advised to limit sun exposure.Schlagwörter case reports; Humans; Skin Neoplasms; Female; Immunosuppressive Agents; Azathioprine; Sunlight; Adult; Inflammatory Bowel DiseasesBergenmar, M.; Brandberg, Y. (2001): Sunbathing and sun-protection behaviors and attitudes of young Swedishadults with hereditary risk for malignant melanoma. In: Cancer Nurs, Jg. 24, H. 5, S. 341–350. AbstractThe aim of the study was to describe attitudes toward sunbathing and sunprotection, to examine sun-related behaviors, and to present an effort to changesun-related behaviors among young adults without a cancer diagnosis inmelanoma-prone families. Ten patients were interviewed, and questionnaires weresent on 3 occasions during a 15-month period to the total population (n = 87)meeting the inclusion criteria. Data from interviews and questionnaires showedextensive ultraviolet-exposure behaviors in this high-risk group for melanoma,although not always expressed in terms of sunbathing. When asked aboutsunbathing, 1/3 reported sunbathing "Often" or "Very often," despite a decrease insunbathing during the study period. In addition, 35% reported current sun bed use.The most important reason for sunbathing was attractiveness. The risk of gettingskin cancer was the most important reason to refrain from sunbathing. The majorityestimated their own risk for melanoma as equal or lower compared with the generalpopulation. The planned intervention failed due to low attendance. Ultravioletexposure is extensive. The individual perception of personal risk and the motivationto change behaviors are important factors to consider when designing a preventiveprogram. Interest for group information was low in this age group.Schlagwörter research support, non-u.s. gov‘t; Genetic Predisposition to Disease; Humans; SkinNeoplasms; Female; Sunburn; Male; Sweden; Melanoma; Analysis of Variance; Adult; Health Knowledge, Attitudes, PracticeBoyd, Alan S.; Shyr, Yu; King, Lloyd E. (2002): Basal cell carcinoma in young women: an evaluation of theassociation of tanning bed use and smoking. In: J Am Acad Dermatol, Jg. 46, H. 5, S. 706–709. AbstractBasal cell carcinomas (BCCs) typically occur in middle-aged to elderly patients butless commonly in younger ones. In our experience, most BCCs seen in patientsyounger than 40 years are found in women. We evaluated 30 women with biopsy-proven BCC and 30 control patients matched for sex, age, and skin type todetermine potential risk factors for this population. Tanning bed visits, pack-years of cigarette smoking, recreational sun exposure, number of blistering sunburns, anduse of sunscreens were determined for both groups. Among patients with a BCC,the histologic type of tumor, site of involvement, method of treatment, follow-upperiod, incidence of recurrence, and presence of actinic keratoses were alsoevaluated. Patients with a BCC had a statistically greater number of pack years of smoking (P =.045), and a greater percentage of these women had experiencedblistering sunburns (P =.028). Although women with a BCC had, on average, almosttwice as many tanning salon visits (152.2 vs 83.1), this was not statisticallysignificant. Sunscreen use and amount of recreational ultraviolet light exposurewere essentially equal between the two groups. Young women with a BCC aremore likely to have a past or current history of cigarette smoking and blisteringsunburns. Repeated exposure to tanning beds may also be a contributory factor.
Sunbeds - CitaviSunbeds - CitaviSunbeds - CitaviSunbeds - CitaviSchlagwörter Incidence; Attitude to Health; Biopsy, Needle; Humans; Middle Aged; SkinNeoplasms; Risk Factors; Ultraviolet Rays; Female; Reference Values; CohortStudies; Heliotherapy; Case-Control Studies; Beauty Culture; Sampling Studies;Smoking; Adult; Age Distribution; Probability; Carcinoma, Basal Cell; AdolescentBrodthagen, H. (1982): Malignant melanoma caused by UV-A suntan bed. In: Acta Derm Venereol, Jg. 62, H. 4,S. 356–357.Schlagwörtercase reports; Neoplasms, Radiation-Induced; Humans; Skin Neoplasms; UltravioletRays; Female; Melanoma; Skin; AdultBuckel, Tamy B. H.; Goldstein, Alisa M.; Fraser, Mary C.; Rogers, Barbara; Tucker, Margaret A. (2006): Recenttanning bed use: a risk factor for melanoma. In: Arch Dermatol, Jg. 142, H. 4, S. 485–488. AbstractBACKGROUND: Individuals at increased risk of melanoma should use sun-protective measures to decrease their risk of developing melanoma.OBSERVATION: We report a case of a 39-year-old patient with a CDKN2Amutation who developed 3 primary melanomas within a few years of initiatingtanning bed use. CONCLUSION: Intense UV exposure as an adult likely contributedto the development of additional primary melanomas in this individual.Schlagwörter case reports; Humans; Shoulder; Skin Neoplasms; Risk Factors; Diagnosis,Differential; Ultraviolet Rays; Mutation; Melanoma; Male; research support, u.s.gov‘t, p.h.s.; Beauty Culture; Leg; Adult; Cyclin-Dependent Kinase Inhibitor p16; AbdomenBuljan, Marija; Bulat, Vedrana; Situm, Mirna; Mihić, Liborija Lugović; Stanić-Duktaj, Sandra (2008): Variations inclinical presentation of basal cell carcinoma. In: Acta Clin Croat, Jg. 47, H. 1, S. 25–30. AbstractBasal cell carcinoma (basalioma, BCC) is the most common skin cancer and themost common human malignancy in general, with a continuously increasingincidence. In most cases, BCC develops on chronically sun-exposed skin in elderlypeople, most commonly in the head and neck region. Besides chronic UV radiation,other risk factors for the development of BCC include sun bed use, family history of skin cancer, skin type 1 and 2, a tendency to freckle in childhood,immunosuppression, previous radiotherapy, and chronic exposure to certain toxicsubstances such as inorganic arsenic. There are numerous variations in clinicalpresentation of BCC, such as nodular BCC, ulcerating BCC, pigmented BCC,sclerosing BCC, superficial BCC, and fibroepithelioma of Pinkus. Each varies interms of clinical presentation, histopathology and aggressive behavior. Treatmentmodalities for BCC include surgical excision, cryosurgery, curettage,electrodessication, radiotherapy, photodynamic therapy, topical cytostatics, andimmunomodulators. If left untreated or inadequately treated, BCC may becomeinvasive and locally destructive, although it very rarely metastasizes. Due to theextremely high incidence of BCC, medical professionals should be familiar with itsmanifold clinical presentations.Schlagwörter Humans; Skin Neoplasms; review; Carcinoma, Basal Cell(1993): Careful fun in the sun. Hospital measures UV rays and issues skin cancer advisories. M.D. AndersonCancer Center, Houston, TX. In: Profiles Healthc Mark, H. 54, S. 2–7.SchlagwörterHumans; Skin Neoplasms; Budgets; Hospital Bed Capacity, 500 and over;Ultraviolet Rays; Texas; Cancer Care Facilities; Health EducationChan, Henry H. L.; Yang, C. H.; Leung, Joseph C. K.; Wei, W. I.; Lai, K. N. (2007): An animal study of theeffects on p16 and PCNA expression of repeated treatment with high-energy laser and intense pulsed lightexposure. In: Lasers Surg Med, Jg. 39, H. 1, S. 8–13. AbstractBACKGROUND AND OBJECTIVE: Non-ablative skin rejuvenation treatments thatinvolve the use of laser/light sources together with cooling devices have gainedmuch popularity in recent years due to the lack of down time that is associated withthem. One important but neglected issue is long-term safety. Does the repeated use
Sunbeds - CitaviSunbeds - CitaviSunbeds - CitaviSunbeds - Citaviof non-ablative skin rejuvenation lead to photoaging? Are we creating another sun-bed phenomenon? Recently, we performed an in vitro study to examine the effect of sub-lethal QS 755 nm lasers on the expression of p16INK4a on melanoma celllines, and found that sub-lethal laser damage could increase DNA damage, whichled to an increase in p16 expression. Our objective was to assess the cutaneouseffect of repeated exposure to high-energy lasers and intense pulsed light sourceson male Institute of Cancer Research (ICR) mice. STUDY DESIGN/MATERIALS AND METHODS: Twenty-eight male ICR mice were divided into four groups. Other than the control group, all groups received either laser (585 nm pulsed dye laser or 1,320 nm Nd:YAG laser) or intense pulsed light (IPL) treatment. All four groupswere anesthetized with a mixture of Hypnorm/Dormicum before treatment. Theanimals were irradiated twice a week for 6 months. Signs of toxicity such asmortality and weight loss were checked once a week. Skin tumor formation wasevidenced by lesions of greater than 1 mm in diameter that persisted for 2 weeks. At the end of the 6 months, the expression of proliferating cell nuclear antigen(PCNA) and p16 in the mouse skin was determined by immunohistochemicalstaining and immunoblotting using specific monoclonal antibodies for mouse PCNAand p16. The results were expressed as mean +/- standard error of the mean(SEM). Statistical difference was assessed by multiple ANOVA. A P-value of <0.05was considered to be significant. RESULTS: At the end of the 6 months, none of the animals had developed any signs of toxicity such as mortality or weight lost.There was no evidence of tumor formation. There were significant elevations of p16and PCNA in all treated groups as compared to the control group (ANOVA P <0.05). This particularly applied to the group that was treated with the 1,320 nmNd:YAG laser. CONCLUSION: The repeated use of high-energy laser and intensepulsed light source did not cause any toxicity in mice. The changes in p16 andPCNA imply that further studies are necessary to consider the implications of repeated exposure to longer wavelength radiation in human skin.Schlagwörter Lasers; Animals; Genes, p16; Male; Skin; Mice, Inbred ICR; Time; Proliferating CellNuclear Antigen; Laser Therapy, Low-Level; Mice; Biological MarkersChen, Weiliang; Li, Jingsong; Yang, Zhaohui; Yongjie, Wang; Zhiquan, Wang; Wang, Youyuan (2008): SMASfold flap and ADM repair of the parotid bed following removal of parotid haemangiomas via pre- andretroauricular incisions to improve cosmetic outcome and prevent Frey‘s syndrome. In: J Plast Reconstr AesthetSurg, Jg. 61, H. 8, S. 894-9; discussion 899-900. AbstractThe growth of parotid haemangiomas during the proliferative phase may be rapidand unpredictable. Involution often takes many years, with attendant psychologicalsequelae to the child. Although conservative management is usually proposed for parotid haemangiomas occurring in infancy, this may not be particularly helpful andthe haemangioma difficult to conceal. The purpose of this study was to evaluate thereliable and aesthetic benefit of using a superficial musculoaponeurotic system(SMAS) fold flap and allograft dermal matrix (ADM) repair of the parotid bedfollowing parotid haemangiomas via pre- and retroauricular incision. Forty-threepaediatric patients (33 boys and 10 girls) with haemangiomas involving the parotidgland underwent total parotidectomy using a pre- and retroauricular approach withintraoperative placement of ADM within the parotid bed. They further underwentrepair of the parotid bed with SMAS fold flaps. A panel of three plastic surgeonsassessed the cosmetic outcomes. All of the patients were evaluated using a shortquestionnaire; postoperative gustatory sweating was assessed using a modificationof Minor‘s starch-iodine test.Schlagwörter Child, Preschool; Humans; Treatment Outcome; Esthetics; Parotid Gland;Hemangioma; Tomography, X-Ray Computed; Female; Infant; Sweating, Gustatory;Male; evaluation studies; Surgical Flaps; Skin Transplantation; ReconstructiveSurgical Procedures; Parotid NeoplasmsChernoff, Karen A.; Bordone, Lindsey; Horst, Basil; Simon, Katherine; Twadell, William; Lee, Keagan et al.

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