Generic Name(Brand Name)IndicationDosage,Route,FrequencyMechanism of ActionAdverse ReactionContraindicationNursing ResponsibilityOxytocin(Pictopin,Syntocinon)Indication:Induction of labor at term; control of postpartum bleeding;adjunctivetherapy inmanagement of abortion
Forstimulation of labor:
10 units(1ml) of druginfused in 1LD5LRS beforedeliver
ForReduction of Postpartumbleeding
: 1amp after delivery of placenta
Oxytocin↓Causes potent andselectivestimulation of uterine andmammary glandsmooth muscles↓ producing sustainedcontractions↓Induces labor andmilk ejection andreduces post partum bleedingCardiovascular:hypertension;increased heart rate,systemic venousreturn, and cardiacoutput, andarrhytmiasCNS: seizures,coma from water intoxicationGastrointestinal: Nausea, vomiting,GU: titanic uterinecontractions,abruption placentae, impaireduterine blood flow, pelvic hematomaHematologic:afibrinogenemiaRespiratory:anoxia, asphyxia> Contraindicated in patients hypersensitiveto the drug or any of its component.> Also contraindicatedin cephalopelvicdisproportion or delivery that requiresconversion, as intranverse lie; in fetaldistress when deliveryisn’t imminent; in prematurity and insevere toxemia,hypertonic uterine patterns, total placenta previa or vasa previa.> Also contraindicatedin fetal distress.
> Monitor and recorduterine contractions, heartrate, BP, intrauterine pressure, fetal heart rate,and blood loss q15.>Be alert for adversereaction>Monitor I/O. Antidiureticeffect may lead to fluidoverload, seizures, andcoma>never give oxytocinsimultaneously by morethan one route.>have 20% solutionmagnesium sulfateavailable for relaxation of the myometrium.>If contractions are lessthan 2 minutes apart, if they’re above 50mm Hg,or if they last 90secondsor longer, stop infusion,and turn patient on her side, and notify physicianor midwife.
Maniulit, Joeanne Mae A. N-304 Group 3