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Highlights of Jian Zhou’s Life
Jing Zhou
Jian Zhou (1957-1999), a famous molecular biologist and virologist, has become a legend for his invention tothe first cancer vaccine in the medical history.Jian was born in Hangzhou, China, in 1957. After finishing his secondary education, he was sent to work in afactory. In 1977 when China resumed the tertiary entrance examination, he was admitted to study medicine atWenzhou Medical College where he obtained his MBBS degree. He then continued to study his Master’sdegree at Zhejiang Medical University where he became interested in pathology. In 1985, he studied to pursuehis Ph D degree at Henan Medical University where he became very interested in molecular biology andvirology for human papillomavirus (HPV) and cancer research. In 1994, Jian was awarded with a degree of Doctor of Medicine by the University of Queensland.From 1987 to 1999, the year in which Jian’s own life was shortened by sudden illness, he held numerousresearch positions, from Postdoctoral Training Fellow, at Beijing Medical University, Beijing, China; ResearchFellow of ICRF Tumour Virus Laboratory, Department of Pathology, University of Cambridge, UK; NHMRCSenior Research Officer, Centre for Immunology and Cancer Research, Department of Medicine, University of Queensland, Brisbane, Australia; Assistant Professor, Head of Papillomavirus Structure Protein Laboratory,Loyola University Medical School, Chicago, USA; Lions Principal Research Fellow & Head of thePapillomavirus Structure Protein Laboratory, Centre for Immunology and Cancer Research, Department of Medicine, Princess Alexandra Hospital, University of Queensland. From 1992 to 1999, Jian was granted withapproximately twenty (20) research projects and eleven (11) patents.It is clear now that 99.8% of cervical cancer is caused by infection of HPVs, which are small DNA viruses.For decades, scientists, among whom are Jian and his wife Xiaoyi Sun, were working on this virus, but couldnot succeed in culture the virus in the laboratory. It was not until 1991 that Jian and his wife finally expressedthe first HPV virus-like particle in their laboratory! This was a vital contribution to the success of today’scervical cancer vaccine, the application of which has been suggested capable of wiping out the cervical cancer within a generation.However, in real life, Jian was more than just a biologist. In his honour, this collection of memoirs hasrecorded Jian as a dedicated scientist, a devoted son, a loving husband, a caring father and a faithful friend.
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Jing Zhou, Brisbane, Australia
 
 
周健生平周健生平周健生平周健生平
 
孙小依孙小依孙小依孙小依
 
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1957年，出生于浙江杭州。
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1982年，毕业于浙江温州医学院获医学学士学位。
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1984年，毕业于浙江医科大学（现浙江大学）获病理硕士学位。
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1985年，考入河南医科大学病理系读博士， 致力于人乳头瘤病毒（简称HPV）的研究。1987年获理学博士学位。博士生期间得到北京病毒所的支持，开始在国际权威性学术刊物上发表论文。科研成果获国家科技进步二等奖。
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1988年，进入北京医科大学（现北京大学）生化系博士后流动站做研究。其间赴位于剑桥大学的帝国癌症研究基金会（ICRF）肿瘤与病毒实验室做研究工作。
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1990 年，移民澳大利亚定居布里斯本。加入Ian Frazer领导的位于亚历山大公主医院的昆士兰大学癌症研究中心继续HPV研究。
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1991年，率先用DNA重组技术人工体外合成了HPV病毒样颗粒。该颗粒就是癌症疫苗的基础。1991年6月，昆士兰大学为这项发明成果申请了专利。CSL、Merck公司得到专利授权。
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1994年，获昆士兰大学医学博士学位。同年到芝加哥Loyola医科大学任助理教授，仍继续HPV研究，任博士研究生导师。
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1996年，回昆士兰大学医学系癌症免疫研究中心，任Lions 主任研究员和HPV病毒学研究室，担任博士研究生导师。至1998年，周健已经有近十项发明专利。同年，他获得3项澳大利亚国家健康与医疗委员会（NHMRC）的研究经费，加上其他经费，成为当时昆士兰大学历史上在一年内申请到经费最多的一位研究人员。周健还积极推动中国和澳大利亚两国之间学术交流。
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1999年3月，因长期超负荷的工作，过度疲劳，突发疾病去世，年仅42岁。追悼会挽联“一世伟业真真切切科研巨擘 毕生勤奋坦坦荡荡学者楷模”是他的真实写照。
 
 
学士学位证书
 
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