Preparation: No additional preparation is required.Infusion: Administer by direct injection or into the tubing of a running IV, each 10mg over 3-5 min.V-site incompatibilities: Do not give with nafcillinAdverse Effects:
Sedation. Clamminess, sweating headache, nervousness, restlessness,depression, crying, confusion, faintness, hostility, unusual dreams, hallucinations,euphoria, dysphoria, unreality, dizziness, vertigo, floating feeling, feeling of heaviness,numbness, tingling, flushing, warmth, blurred vision.
Hypotension, Hypertension, bradycardia, tachycardia
Itching, burning, urticaria
Nausea, vomiting, cramps, dyspepsia, bitter taste, dry mouth
Respiratory depression, dyspnea, asthma
Drug class:Phenothiazine, Dopaminergic bloking agent, Antihistamine, Antiemetic, Anti-motion sickness agent, Sedative/hypnotic.Therapeutic Actions:Selectively blocks H1 receptors, diminishing the effects of histamine on cells of the upper respiratory tract and eyes and decreasing the sneezing, mucus production,itching and tearing that accompany allergic reactions in sensitized people exposed toantigens; blocks cholinergic receptors in the vomiting center that are believed to mediatenausea and vomiting caused by gastric irritation, by input from the chemoreceptor trigger zone; depress the RAS, including the parts of the brain involves in wakefulness.Indications:
Symptomatic relief of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis; mild, uncomplicated urticaria andangioedema; amelioration of allergic reactions to blood or plasma;dermatographism, adjunctive theraphy.
Treatment and prevention of motion sickness; prevention and control of nausea and vomiting associated with anesthesia and surgery.