Many manufacturers have their own engineering design and qualiﬁcation stan-dards and requirements may vary from one manufacturer to the next. Design parameters should, therefore, be set realistically for each project, with a viewto creating a cost-effective design, yet still complying with all regulatorystandards and ensuring that product quality and safety are not compromised.
The three primary aspects addressed in this manual are the roles that theHVAC system plays in product protection, personnel protection and environmental protection (Fig. 1).
The guidelines address the various system criteria according to the sequence setout in this diagram
GMP, Good manufacturing practice.
Contamination(product & staff)Prevent contactwith dust Avoid dustdischargeProtect from productcross-contaminationPrevent contact withfumes Avoid fumedischargeCorrect temperature& humidity Acceptable comfortconditions Avoid effluentdischarge