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Clockwork Genes

Clockwork Genes

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Published by: Tyler on May 02, 2008
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10/14/2011

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HOLIDAY LECTURES ON SCIENCE HOLIDAY LECTURES ON SCIENCE
Presented as a public service by the Howard Hughes Medical Institute
An activity and content guide on the topic of biological clocks based on lectures by
MICHAEL ROSBASH,P
H
.D.JOSEPH S.TAKAHASHI,P
H
.D.
HHMI Investigator and Walter and MaryElizabeth Glass Professor of Neurobiology and Physiology at Northwestern University, and Professor of Neurology at Northwestern University Medical SchoolHHMI Investigator and Professorof Biology at Brandeis University, andAdjunct Professor of Molecular Biology atMassachusetts General Hospital, Boston
TEACHER AND STUDENT GUIDE
 
1
Viewing and Participating in This Year’s Lectures
2
About This Guide0
3
Introduction to Biological Clocks0
5
LIVES IN SCIENCE
Michael Rosbash, Ph.D.Biography9Career Highlights12Joseph S. Takahashi, Ph.D.Biography13Career Highlights16
CLASSROOM CONNECTIONS
Lecture One – Biology in Four Dimensions0Summary19119Key Concepts2020Challenge Questions21Lecture Two – Unwinding Clock GeneticsSummary23Key Concepts24Challenge Questions25Lecture Three – PERfect TIMingSummary27Key Concepts28Challenge Questions29Lecture Four – The Mammalian TimekeeperSummary31Key Concepts33Challenge Questions33Web and Print Resources on Biological Clocks35
TEACHER-DIRECTED CLASSROOM ACTIVITIES
Activity One Charting StudentsKnowledge: The KWL Chart410Activity Two Biological Clock Scavenger Hunt43Activity Three Body Temperature and Reaction Time Laboratory47Correlations to Advanced Placement Biology Curriculum51AP Laboratory Extension53Teacher Guidelines for Answering Challenge Questions59
Holiday Lectures Resources
Resources on the Holiday Lectures Website65Holiday Lectures Exhibit 200067Previous Lectures67
Howard Hughes Medical Institute
Overview of Programs71Trustees, Officers, and Staff73Web Index77
Acknowledgments
79
 ABLEOF 
ONTENTS
 
2
To view the lectures
 —The 2000 lectures will be available live starting at 10:00 a.m. ESTon December 4 and 5 via satellite in the United States, and worldwide via webcast from
WWW
.
HOLIDAYLECTURES
.
ORG
/
WEBCAST
.
If you plan to view the live satellite broadcast, pleaserefer to the back inside cover of this guide for information on satellite coordinates andtelephone numbers in case of technical problems. If you plan to view the live webcast, makesure that RealPlayer has been successfully installed on your computer ahead of time. AfterDecember 5, the webcast will be available on demand. For more information about thewebcast, visit the Holiday Lectures website at
WWW
.
HOLIDAYLECTURES
.
ORG
/
WEBCAST
.You willfind instructions and a link to the “Technical Tips” page, which is also available directly at
WWW
.
HHMI
.
ORG
/
GRANTS
/
HELP
.
HTM
.
To ask questions
 —Students and teachers will have the chance to ask questions directly to Drs. Rosbash and Takahashi by participating in live Q&A sessions to be held each day from1:30 p.m. – 2:30 p.m. EST on both the satellite broadcast and the webcast. Questions maybe phoned in live to 1-800-223-9050, e-mailed in advance to asklive@hhmi.org, or asked viaour chat software at
WWW
.
HOLIDAYLECTURES
.
ORG
/
ASKLIVE
2000
.
To view the January rebroadcast
 —If your school receives its satellite programming via the Channel One Network and you have no other satellite capacity, you will not be ableto receive the Holiday Lectures at the times and coordinates listed on the inside back coverof this guide. However, Channel One Connection will rebroadcast Lectures 1 and 2 onJanuary 17, 2001, and Lectures 3 and 4 on January 24, 2001. Please ask your school’s media specialist to tape the Channel One rebroadcast.See your January Channel One TeachWorld.com poster for more information.
To order educational materials
 —Videotapes of the lectures and a detailed index tothe lectures will be available a few months after the live event. In addition, theinteractive demonstrations are available on the Web and later on CD-ROMs.To ord e rthese materials from the 2000 or earlier Holiday Lectures, visit the HHMI website at
WWW
.
HOLIDAYLECTURES
.
ORG
/
ORDER
and fill out an order form.
 V 
IEWINGAND
P
 ARTICIPATINGIN
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 Y
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ECTURES

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