Computation:345 U/L / 520 U/L =
The computed value is in borderline case, which gives us a slight confusion if the pleuralfluid obatained is wether a transudate or an exudate. But the group still stands that theobtained fluid is an exudate.
3. Classify this pleural fluid specimen as a transudate or exudate and state twophysiologic mechanisms that can cause this type of effusion.
The group stands that the obtained fluid is an
The following supports our conclusion:
The ratio of pleural fluid protein to serum protein is greater than 0.5.
The ratio of pleural fluid LDH and serum LDH is greater than 0.6.
leural fluid LDH is more than two-thirds normal upper limit for serum.
Malignant Pleural Effusions
Malignant pleural effusions are generally treated to relieve shortness of breath and/or chest pain caused by the presence of mesothelioma (caused by asbestosis) or neoplasmsthat have metastasized from elsewhere in the body; the lungs or breast are usually the primary site. Metastatic involvement is far more frequent than primary malignancies of the pleura (mesotheliomas).Mechanism of malignant pleural effusion:a.
increased capillary permeability as a result of inflammation or disruptiopn of thecapillary endothelium b.
impaired lymphatic drainage or decreased drainage in the pulmonary veinsecondary to obstrustion by tumor c.
direct invasion of the pleural space by the tumor
What is the possible diagnosis of the patient? Explain
Since pleural effusions are associated with many systemic disorders. We conclude thatthe patient suffers from mesothelioma. Due to the exposure of the construction worker toasbestos, a naturally occurring silicate minerals exploited commercially for their desirable physical properties and for The inhalation of asbestos fibres can cause serious illnesses, including malignant lungcancer, mesothelioma (a rare malignant neoplasm strongly associated with exposure toasbestos), and asbestosis (a type of pneumoconiosis)Malignant pleural effusion is a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue (pleura) lining the outside of the lung and