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Imhotep Virtual Medical School March, 20101
IVMSBMS GENERAL PRINCIPLES USMLE WEB MAPS
COMPONENT VI: GENERAL PATHOLOGY: PATHOGENESIS ANDBIOLOGY OF TISSUE RESPONSE TO DISEASEdeals withinflammation (cells & mediators), reparative process and thebasic concepts in neoplasia including carcinogenesis, tumorimmunology and cancer epidemiology, prevention and control.
6.1. INFLAMMATION (CELLS AND MEDIATORS)IVMS-General Pathology- Inflammation PPt. http://ocw.tufts.edu/Course/51/lecturenotes WebPath-Inflammation Index HTML. Page (excellent, most comprehensive pathologic basis of inflammation
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highly recommended)http://en.wikipedia.org/wiki/Inflammation Acute inflammation and mediator systems (pharmacologic mediators)IVMS-Anti-Inflammatory and Autacoid Pharmacology- NSAIDs Vascular response to injury (including mediators) Inflammatory cell recruitment (adherence andcell migration) and phagocytosishttp://mayoresearch.mayo.edu/vmiller_lab/endothelial.cfm Bactericidal mechanisms and tissue injuryClinical manifestations (including pain, fever, leukocytosis, leukemoid reaction, and chills)http://www.epathoplus.com/inflammation.htm Chronic inflammationCHRONIC INFLAMMATION AND WOUND HEALING IVMS Inflammation Notes 6.2. REPARATIVE PROCESSESInflammation and Repair Illustrated Lectures Wound healing, hemostasis, and repair: thrombosis, granulation tissue, angiogenesis, fibrosis,and scar/keloid formationhttp://en.wikipedia.org/wiki/Wound_healing How wounds heal and tumors formRegenerative processes6.3. NEOPLASIAhttp://www.pathguy.com/lectures/unknown.htm http://edcenter.med.cornell.edu/CUMC_PathNotes/Neoplasia/Neoplasia_01.html (excellentclassification of neoplasm)Classification, histologic diagnosishttp://clinlabs.path.queensu.ca/present/dexter/oldneoplasia/ http://www.vet.purdue.edu/vpb/clinpath/vpb555/555cyt3/sld033.htm Grading, and staging of neoplasms
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