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Animation of ATP Synthesis

Animation of ATP Synthesis

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Published by allanlopez_2009

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Categories:Types, Research, Science
Published by: allanlopez_2009 on Mar 24, 2010
Copyright:Attribution Non-commercial

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06/12/2014

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Copyright 1997. Thomas M. Terry, The University of Connecticut.
 
Animation of ATP synthesis in Mitochondria
Step 1:
 
Proton gradient
is built up as a result of NADH (produced from oxidation reactions)feeding electrons into electron transport system.
Copyright 1997. Thomas M. Terry, The University of Connecticut.
 
Animation of ATP synthesis in Mitochondria
Step 1:
 
Proton gradient
is built up as a result of NADH (produced from oxidation reactions)feeding electrons into electron transport system.
Step 2:Protons
(indicated by
+
charge) enter back into the mitochondrial matrix throughchannels in ATP synthase enzyme complex. This entry is coupled to ATP synthesis from ADPand phosphate (P
i
)
 
Go to Animation of electron transport in Mitochondria The schematic diagram above illustrates a mitochondrion. In the animation, watch as H
+
ionsaccumulate in the outer mitochondrial compartment whenever NADH is made from oxidationreactions, generating a proton gradient (upper image). Protons re-enter the cell through the ATPsynthase complex, generating ATP (lower image).Key points:
1.
Protons
are translocated
across
the membrane, from the matrix to theintermembrane space, as a result of electron transport resulting from the formationof NADH by oxidation reactions. (See theanimation of electron transport.) Thecontinued buildup of these protons creates a
proton gradient
.
2.
ATP synthase
is a large protein complex with a proton channel thatallows re-entry of protons.
3.
ATP synthesis
is driven by the resulting current of protons flowingthrough the membrane:
ADP + P
i
---> ATP
Step 2:Protons
(indicated by
+
charge) enter back into the mitochondrial matrix throughchannels in ATP synthase enzyme complex. This entry is coupled to ATP synthesis from ADPand phosphate (P
i
)

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