Dermal cylindroma

Dermal cylindroma Clinical: Sex: mostly female. Location: mostly scalp. Slow-growing, sometimes painful solitary pink or red dermal nodule averaging 1 cm in size. Familial cases are associated with multiple tumors. Such cases may also be associated with facial trichoepitheliomas, and eccrine spiradenomas, called autosomal dominant Brooke-Spiegler syndrome (familial cylindromatosis or turban tumor syndrome). Pathologic features: Presence of numerous scalp lesions is called turban tumor. This is a non-encapsulated dermal tumor not connected to the overlying epidermis. It is composed of numerous lobules of epithelial cells arranged in a jigsaw or mosaic pattern. A prominent red basement membrane-like structure encircles the tumor lobules. Each lobule shows a peripheral lining by dark basaloid cells and an inner larger and paler zone of cells. There are nodular deposits of red material within the lobules as well as focal well-formed ducts. This is a common adnexal tumor of eccrine origin.

M 61, scalp. Fig 1

Fig 2

Fig 3

Deba P Sarma, MD Dermatopathologist, Lakeside Hospital Omaha