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pathoPhysiology of Nephrolithiasis

pathoPhysiology of Nephrolithiasis

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Published by anreilegarde

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Published by: anreilegarde on Mar 28, 2010
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08/15/2013

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NEPHROLITHIASIS : PATHOPHYSIOLOGY
Non modifiable factors:
-Age (64 years old)-Sex (male)
Modifiable factors:
-Diet (unusually high in soy & fishsauce, bagoong, softdrinks, legumes, protein & salt)-Certain meds (Analgesics)-Low fluid intake-Urinary stasis-Smoking & alcoholic drinking-Gouty arthritisRandall’s plaque Nephrocalcinosis on proximaltubuleUric acid(523.83mmoL/L), ammonia phosphate(BUN=16.50mmoL/L), and calciumoxalate stone material deposition on proximalrenal tubuleEpisodes of  pain in sideradiating inthe back  Nidation of crystals or foreign bodies from thesupersaturated urinePyuriaIncrease production of WBCUrinary Tract Infection caused by ureasplitting organismSuper saturation of urine by stone formingconstituents(↓OFI, pH(5)Hyperkalemia(5.62 mmoL/L)

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