Chem 5
Chapter 10The Periodic Table and SomeAtomic PropertiesPart 4November 8, 2002
Noble Prize in Chemistry, 2002
KurtWüthrichJohn B.FennKoichi Tanaka“The Nobel Prize in Chemistry for 2002 is being shared between scientists intwo important fields: mass spectrometry (MS) and nuclear magneticresonance (NMR). The Laureates, John B.Fennand Koichi Tanaka (for MS)and KurtWüthrich(for NMR), have contributed in different ways to the further development of these methods to embrace biological macromolecules. Thishas meant a revolutionary breakthrough, making chemical biology into the "bigscience" of our time. Chemists can now rapidly and reliably identify whatproteins a sample contains. They can also produce three-dimensional imagesof protein molecules in solution. Hence scientists can both "see" the proteinsand understand how they function in the cells.”
http://www.nobel.se/chemistry/laureates/2002/public.html
Mass Spectroscopy for Macromolecules
Electrospray technique
Time-of-flight mass spectrometer
http://www.nobel.se/chemistry/laureates/2002/chemadv02.pdf
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