BACKGROUNDER

The Medtronic Vision 3D Portfolio

Overview

The Vision 3D™ wireless ICD and CRT-D portfolio offers unparalleled depth and breadth of unique clinical options that are built on our industry leading pacing and ICD exclusives. It is theindustry’s most comprehensive family of wireless implantable heart devices.The portfolio brings together Medtronic’s state-of-the-art cardiac rhythm device technology toprovide physicians and patients the devices, services and remote monitoring needed to meetindividual therapy goals:

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Increased Choice of Product – Device options built on industry-leading, exclusivetechnologies allow physicians to select the right product with the right features for eachpatient’s individual health needs.

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Enhanced Feature Depth – Patients have access to Medtronic’s proprietary features acrossthe portfolio of products.

Vision 3D Portfolio Fundamentals

The portfolio includes key Medtronic-proprietary features, which serve as foundational elementsacross the group:

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Shock Reduction – the devices use pacing pulses to painlessly stop dangerous rhythms,while simultaneously preparing to deliver a shock, if needed, to terminate a potentially fatalrhythm.

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Disease Management – data collection and reporting of up to 14 months of clinical deviceinformation, including arrhythmia episodes, therapies delivered, physical activity, pacingactivity and fluid levels, to help better manage the patient’s heart disease.

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Therapy Efficacy – providing effective therapy when needed, whether significantly reducingunnecessary pacing to the right ventricle, or ensuring delivery of CRT for patients withdysynchronous heart.

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Remote Patient Care – collection and reporting of device data through the secure CareLink remote monitoring network, which allows information to be sent to patient’s cardiologist viaa standard phone line, potentially reducing office visits and providing timely alerts to theclinician if a problem arises.

Personalized Care

Medtronic’s Vision 3D portfolio allows physicians to specify the unique feature options needed tomeet their patients’ individual needs. These products continue Medtronic’s legacy of leadership inthe industry by delivering products based on customer feedback and mounting clinical evidence,including:

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MVP®, or Managed Ventricular Pacing – available since 2004, allows doctors to dramaticallyreduce unnecessary pacing to the right ventricle, or the heart’s lower right chamber, and isincluded in all Vision 3D ICDs.1

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OptiVol® Fluid Status Monitoring – a Medtronic exclusive feature that has been available since2004, OptiVol measures intrathoracic impedance in heart failure patients. Using very lowelectrical pulses that travel across the thoracic cavity, the system can measure the level of resistance to the pulses, which correlates with fluid levels. Used in combination with the