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Table Of Contents

Lipid-soluble materials
Membranes Are Asymmetric Structures
Asymmetry of proteins and lipids maintained during membrane assembly
Signal Hypothesis - Entry into ER
Synthesis of secretory proteins
Synthesis of secretory proteins - review
Synthesis of integral membrane protein
Intracellular Transport Vesicles
Signal sequences target proteins to their correct destinations
Active Transport
Hormone Receptors
Two general groups of hormones
Group I Hormones
Group II Hormones
cAMP as Second Messenger
Adenylyl cyclase system
Bacterial toxins irreversibly activate adenylyl cyclase
Superfamily of GTPases
cAMP-dependent protein kinase
cGMP as Second Messenger
Hormones act through calcium
Calmodulin
Receptor tyrosine kinase (RTK) cascade
Non-receptor tyrosine kinase
Signaling crosstalk and convergence
Properties of cancer cells
Agents causing cancer
Radiant Energy
Chemical Carcinogens
Mutagens
DNA and RNA Viruses are Carcinogenic
Oncogenes of retroviruses
Activation of Proto-oncogenes
Promoter Insertion
Enhancer Insertion
Chromosomal Translocations
Gene Amplification
Point Mutation
Oncogenes
Colorectal cancer: A model for cancer development
DNA Repair Systems
Cancer Chemotherapy
Development of new cancer therapies
Classes of Biomolecules Affected in Disease
Rate of Biochemical Alterations
Deficiency or Excess of Biomolecules
Organelle Involvement
Different Mechanisms, Similar Effect
Chromosomal Disorders
Monogenic Disorders
Multifactorial Disorders
Inborn Error of Metabolism
Methods to clone disease genes
Identifying defect in disease gene
Ethical Issues
Molecular Medicine
Gene expression in diagnosis
Treatment for Genetic Diseases
Gene Therapy
Genetic Medicines
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Medical Biochemistry

Medical Biochemistry

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Published by: Dr. Stefan Gruenwald on May 15, 2008
Copyright:Attribution Non-commercial

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08/14/2013

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