February 11,2010DETECTION OF DIABETES USING CHROMATOGRAPHY TECHNIQUEFahmi 20072878241
What is Diebetes?
Glucose is an important source of energy for the body. We obtain glucose either from thediet or from production by the liver. Liver stored or released glucose to maintain theoptimum level of glucose in the blood. Insulin, a hormone synthesized by the pancreas,allows cells to utilize glucose, which reduces blood glucose levels. The more glucose in yourblood, the more insulin the pancreas releases. Diabetes is caused by an inability to properlyprocess glucose, resulting in chronic hyperglycemia. Chronic hyperglycemia results in long-term damage to various organs such as the kidneys, heart, and eyes
There are 3 primary types of diabetes. First is type 1 diabetes or can be called as insulin-dependent diabetes mellitus or juvenile-onset diabetes. It is mainly caused by autoimmune,genetic, and environmental factors and make or involve in the destruction of the insulin-producing cells in the pancreas. Patients require treatment with insulin to regulate bloodglucose back to normal.Second is type 2 diabetes or called adult-onset diabetes. Type 2 diabetes is cause by obesity,genetic factor and age. Person who is diagnosed as type 2 diabetes will develop insulinresistance and require increase insulin production and thus need insulin treatment. Type 2diabetes is the most common diabetes and type 3 diabetes is gestational diabetes whichdevelops during pregnancy.For diabetes patients, blood is use in order to detect or manage diabetes. Certain markersare important in determining amount of sugar in blood or glucose level. One of thoseimportant markers is Hemoglobin A1c (HbA1c) and by using certain tests HbA1c can bemeasured and reflect the blood sugar level.Formation of Insulin