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NBG_status__4262010

NBG_status__4262010

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Published by: lishler on Apr 26, 2010
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NBG (Non-invasive Blood Glucose Measurement)
Know When to Test
I am a systems engineer that has spent more than 12 years developing patented non-invasive blood glucose monitor (NBG) technology. Why draw blood and place it on a strip if you’re blood glucose level is not trending high or low? I believe a temperature difference measured attwo points on your ear can be used to check your blood glucose trend and tell you when youneed to test. Type I diabetics could save $1000 per year and reduce pain from finger sticks. TypeII diabetics would have a new tool to manage their blood glucose levels. Data from this devicecould be sent by Bluetooth to your cell phone or computer where the results would be displayed.
Why Test
People can eat the same quantity of carbohydrates per unit body mass and have very differentglucose levels (figure 1). When I tested today’s meters, I have found errors as high as 29%. Mynew technology is based on temperature measurement as shown in figures 3-6. I used an infraredcamera that cost $100,000 and accurately measured temperature response to
 
glucose in people’shands and ears. The temperature changed in both areas but the ear had more change per unitglucose change.Figure 1 Blood Glucose response after eating (Time T=0)LWI & Associates, Inc. 26 April, 20101
Blood Glucose Levels
 
050100150200250300350400450-60-300306090120150180210240
Time Since Meal
   B   l  o  o   d   G   l  u  c  o  s  e   (  m  g   /   d   l   )
Non DiabeticNon Diabetic LNon Diabetic HType I DiabeticType I Diabetic LType I Diabetic HType II DiabeticType II Diabetic LType II Diabetic H
 
NBG (Non-invasive Blood Glucose Measurement)
Technology behind NBG Invention
Figure 2 Brain converts a high percentage of the glucose in the blood producing heatThe main function of the brain’s hypothalamus is
homeostasis
, or maintaining the body's statusquo. Factors such as blood pressure, body temperature, fluid and electrolyte balance, and bodyweight are held to a precise value called the set-point. Although this set-point can migrate over time, from day to day it is remarkably fixed. To achieve this task, the hypothalamus must receiveinputs about the state of the body, and must be able to initiate compensatory changes if anythingdrifts out of whack. Indirectly or directly the hypothalamus can control every endocrine gland inthe body, and alter blood pressure and blood flow (through vasopressin and vasoconstriction), body temperature, metabolism (through TSH), and adrenaline levels (through ACTH). I foundonly three people in 1 million have a rate of blood glucose change greater than 5mg/dl per minute). NBG measures the temperature difference four times per minute and then can displaythis rate of change in chart or tabular form. For a fee this data can also be sent via the Internet toLWI & Associates, Inc. for review and transmission of “Desktop” (computer) alerts to telldiabetics and others (parents of young diabetics for example) that a test is required. Prototypes of the final product configuration are being built now.
 
Figures 3-6 show how the ear temperatureincreases (more red in the pictures) as more heat comes to the ear from the blood leaving the brain.LWI & Associates, Inc. 26 April, 20102
 
NBG (Non-invasive Blood Glucose Measurement)TVS 8500 IR CameraCamera SpecificationsRange AccuracyResolution-40C to 200C 2C .020C10C to 50C .5C .010CLWI & Associates, Inc. 26 April, 20103

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