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Potential of Rosemary Oil to Be Used in Drug-resistant Infections

Potential of Rosemary Oil to Be Used in Drug-resistant Infections

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Objective: To evaluate the antimicrobial activity potential of the essential oil of rosemary specifically for its efficacy against the drug-resistant mutants of Mycobacterium smegmatis, Escherichia coli, and Candida albicans.
Method: Antibacterial, antifungal, and drug resistance-modifying activity was evaluated both qualitatively and quantitatively following disc diffusion and broth dilution assay procedures.
Results: The rosemary essential oil was found to be more active against the gram-positive pathogenic bacteria except E faecalis and drug-resistant mutants of E coli, compared to gram-negative bacteria. Similarly, it was found to be more active toward non-filamentous, filamentous, dermatophytic pathogenic fungi and drug-resistant mutants of Candida albicans.
Conclusion: Our findings suggest that characterization and isolation of the active compound(s) from the rosemary oil may be useful in counteracting gram-positive bacterial, fungal, and drug-resistant infections.
Objective: To evaluate the antimicrobial activity potential of the essential oil of rosemary specifically for its efficacy against the drug-resistant mutants of Mycobacterium smegmatis, Escherichia coli, and Candida albicans.
Method: Antibacterial, antifungal, and drug resistance-modifying activity was evaluated both qualitatively and quantitatively following disc diffusion and broth dilution assay procedures.
Results: The rosemary essential oil was found to be more active against the gram-positive pathogenic bacteria except E faecalis and drug-resistant mutants of E coli, compared to gram-negative bacteria. Similarly, it was found to be more active toward non-filamentous, filamentous, dermatophytic pathogenic fungi and drug-resistant mutants of Candida albicans.
Conclusion: Our findings suggest that characterization and isolation of the active compound(s) from the rosemary oil may be useful in counteracting gram-positive bacterial, fungal, and drug-resistant infections.

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Published by: InnoVision Health Media on May 13, 2010
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03/19/2013

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