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Preparation of [3H]-Labeled Ohmefentanyl and Opioid Receptor Binding Studies - Acta Pharm Sin 17(9), 658-662 (1982) - Acta Pharmaceutica Sinica

Preparation of [3H]-Labeled Ohmefentanyl and Opioid Receptor Binding Studies - Acta Pharm Sin 17(9), 658-662 (1982) - Acta Pharmaceutica Sinica

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Preparation of [3H]-Labelled Ohmefentanyl and Opioid Receptor Binding Studies - Acta Pharm Sin 17(9), 658-662 (1982)
Title: Preparation of [3H]-Labeled N-[1-(B-hydroxy-B-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropionamide and studies of its binding with opiate receptors of mouse brain
Authors: Zhou De-he, Ni Chong-hu, Wu Yi-zhi, Li Zhi-yi, Liu Jing-zhi, Tang Guo-zhong, and Zhao Xia-ling
Journal: Acta Pharmaceutica Sinica, Acta Pharm Sin, APS, Acta. Pharm. Sin.
Issue: Sept 1982
Vol. XVII, No. 9
Language: Chinese
English Abstract at end of article
KEYWORDS:
pharmacophore, mutagenesis, pharmacy, pharmaceutical, Fentanyl, Analgesics, oxirane, Piperidine, Piperidone, 4-Anilidopiperidine, 4-Anilinopiperidine, Anilinopiperidine, Anilidopiperidine, Aminomethano Desilyation Cyclization, opioid, sufentanil, carfentnail, lofentanil, acetylfentanyl, 3-methylfentanyl, 3MF, TMF, AMF, alphamethylfentanyl, Ohmefentanyl, beta-hydroxy, alpha-methyl, Mefentanyl, 4-methoxymethylcarbonyl, 4-methoxycarbonyl, 4-substituted piperidines, 4,4-disubstituted piperidines, 4-piperidines, 4-substituted fentanyl, 4,4-disubstituted fentanyl, fentanil, phentanyl, phentanil, N-phenylethyl-4-piperidon e, N-phenethyl-4-piperidone, piperid-4-one, piperidinone, N-phenethyl-4-piperidinone, N-phenylethyl-4-piperidin one, piperidin-4-one, NPP, ANPP, fentanyl synthesis, opioid synthesis, opiate, mu opioid receptor, MOR, u opioid receptor, u receptor, mu receptor, mu, opioid analgesic, Sigfreid, Sigfried fentanyl synthesis, opiate alkaloid, poppy alkaloid, heroin, methadone, buprenorphine, subutex, suboxone, Swern Oxidation, controlled substance, NaBH4 reduction, reducing agents, LiAlH4, lithium aluminum hydride, sodium borohydride, adam's catalyst, PtO, platinum oxide, catalytic hydrogenation, N-debenzylation, Pd/C, palladium over carbon, platinum on carbon, 4-propionanilidopiperidin e, morphine, morphine-like analgesics, Paul Janssen, PAJ Janssen, Paul AJ Janssen, P. Janssen, P.A.J. Janssen, Janssen, Janssen Pharmaceuticals, Janssen Pharmaceutica, Belgian, Belgium, 4-phenylpiperidines, piperidones, piperidine, morpholine, organic chemistry, organic synthesis, novel organic synthesis, novel analgesic agent, clandestine drug synthesis, drug manufacture, fentanyl manufacture, opiate opioid synthesis, analgesic, analgetic, synthesis of fentanyl, fentanyl syntheses, review of fentanyl chemistry, fentanyl chemistry, 4-anilinopiperidine chemistry, 4-propionanilinopiperidine chemistry, 4-anilidopiperidine, piperidine chemistry, nitrogen chemistry, heterocyclic nitrogen compounds, organic compounds, opioid chemistry, opioid synthesis, fentanyl syntheses, structural analogues, analogs, fentanyl analog, fentanyl analogues, fentanyl analogs, N-arylalkylpiperidines, 4-phenylpiperidine, carfentanil, sufentanil, lofentanil, alphamethylfentanyl, ohmefentanyl, TMF, 3-methylfentanyl, 4-anilidopiperidines, piperidones, NPP, ANPP, Sigfried synthesis, narcotic analgesics, pharmacology, opiate, pharmaceuticals, opioid analgesics, organic chemistry, medicinal chemistry, analgetics, drug synthesis, mu opioid ligands, mu receptor, agonists, antagonists, agonist-antagonists, 4-anilinopiperidines, phenylpiperidines, piperidin-4-ones, 4-piperidones, Paul Janssen, Janssen Pharmaceutica, Brifentanil, 3MF, a-methylfentanyl, AMF, opioid pharmacology, opioid synthesis, fentanyl synthesis, novel synthesis, organic synthesis procedures, fentanyl chemistry review, pharmacodynamics, pharmacokinetics, fentanyl potency, fentanyl dose conversion, fentanyl analogs, fentanyl analogues, N-phenethyl-4-piperidone, 1-phenethyl-4-piperidone
APS - Acta Pharmaceutica Sinica – Acta Pharm. Sin.
Preparation of [3H]-Labelled Ohmefentanyl and Opioid Receptor Binding Studies - Acta Pharm Sin 17(9), 658-662 (1982)
Title: Preparation of [3H]-Labeled N-[1-(B-hydroxy-B-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropionamide and studies of its binding with opiate receptors of mouse brain
Authors: Zhou De-he, Ni Chong-hu, Wu Yi-zhi, Li Zhi-yi, Liu Jing-zhi, Tang Guo-zhong, and Zhao Xia-ling
Journal: Acta Pharmaceutica Sinica, Acta Pharm Sin, APS, Acta. Pharm. Sin.
Issue: Sept 1982
Vol. XVII, No. 9
Language: Chinese
English Abstract at end of article
KEYWORDS:
pharmacophore, mutagenesis, pharmacy, pharmaceutical, Fentanyl, Analgesics, oxirane, Piperidine, Piperidone, 4-Anilidopiperidine, 4-Anilinopiperidine, Anilinopiperidine, Anilidopiperidine, Aminomethano Desilyation Cyclization, opioid, sufentanil, carfentnail, lofentanil, acetylfentanyl, 3-methylfentanyl, 3MF, TMF, AMF, alphamethylfentanyl, Ohmefentanyl, beta-hydroxy, alpha-methyl, Mefentanyl, 4-methoxymethylcarbonyl, 4-methoxycarbonyl, 4-substituted piperidines, 4,4-disubstituted piperidines, 4-piperidines, 4-substituted fentanyl, 4,4-disubstituted fentanyl, fentanil, phentanyl, phentanil, N-phenylethyl-4-piperidon e, N-phenethyl-4-piperidone, piperid-4-one, piperidinone, N-phenethyl-4-piperidinone, N-phenylethyl-4-piperidin one, piperidin-4-one, NPP, ANPP, fentanyl synthesis, opioid synthesis, opiate, mu opioid receptor, MOR, u opioid receptor, u receptor, mu receptor, mu, opioid analgesic, Sigfreid, Sigfried fentanyl synthesis, opiate alkaloid, poppy alkaloid, heroin, methadone, buprenorphine, subutex, suboxone, Swern Oxidation, controlled substance, NaBH4 reduction, reducing agents, LiAlH4, lithium aluminum hydride, sodium borohydride, adam's catalyst, PtO, platinum oxide, catalytic hydrogenation, N-debenzylation, Pd/C, palladium over carbon, platinum on carbon, 4-propionanilidopiperidin e, morphine, morphine-like analgesics, Paul Janssen, PAJ Janssen, Paul AJ Janssen, P. Janssen, P.A.J. Janssen, Janssen, Janssen Pharmaceuticals, Janssen Pharmaceutica, Belgian, Belgium, 4-phenylpiperidines, piperidones, piperidine, morpholine, organic chemistry, organic synthesis, novel organic synthesis, novel analgesic agent, clandestine drug synthesis, drug manufacture, fentanyl manufacture, opiate opioid synthesis, analgesic, analgetic, synthesis of fentanyl, fentanyl syntheses, review of fentanyl chemistry, fentanyl chemistry, 4-anilinopiperidine chemistry, 4-propionanilinopiperidine chemistry, 4-anilidopiperidine, piperidine chemistry, nitrogen chemistry, heterocyclic nitrogen compounds, organic compounds, opioid chemistry, opioid synthesis, fentanyl syntheses, structural analogues, analogs, fentanyl analog, fentanyl analogues, fentanyl analogs, N-arylalkylpiperidines, 4-phenylpiperidine, carfentanil, sufentanil, lofentanil, alphamethylfentanyl, ohmefentanyl, TMF, 3-methylfentanyl, 4-anilidopiperidines, piperidones, NPP, ANPP, Sigfried synthesis, narcotic analgesics, pharmacology, opiate, pharmaceuticals, opioid analgesics, organic chemistry, medicinal chemistry, analgetics, drug synthesis, mu opioid ligands, mu receptor, agonists, antagonists, agonist-antagonists, 4-anilinopiperidines, phenylpiperidines, piperidin-4-ones, 4-piperidones, Paul Janssen, Janssen Pharmaceutica, Brifentanil, 3MF, a-methylfentanyl, AMF, opioid pharmacology, opioid synthesis, fentanyl synthesis, novel synthesis, organic synthesis procedures, fentanyl chemistry review, pharmacodynamics, pharmacokinetics, fentanyl potency, fentanyl dose conversion, fentanyl analogs, fentanyl analogues, N-phenethyl-4-piperidone, 1-phenethyl-4-piperidone
APS - Acta Pharmaceutica Sinica – Acta Pharm. Sin.

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Published by: jtjdp4 on May 14, 2010
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