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  • Henoch-Schönlein Purpura (HSP)

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    Emily Eresuma
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    Henoch-Schönlein Purpura (HSP) is the most common vasculitis of childhood that typically occurs between ages 5 and 10 and is thought to be triggered by an infection. It is characterized by IgA deposits that can affect the skin, joints, kidneys, and GI system. Joint involvement occurs in 60-84% of cases, primarily in the ankles and knees. Kidney involvement presents as hematuria and/or proteinuria in 5-20% of cases and carries risks for long-term renal issues. GI involvement is seen in 50-80% of cases and can include abdominal pain, bloody diarrhea, and rare complications such as intussusception or perforation.

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    Henoch-Schönlein Purpura (HSP) is the most common vasculitis of childhood that typically occurs between ages 5 and 10 and is thought to be triggered by an infection. It is characterized by IgA deposits that can affect the skin, joints, kidneys, and GI system. Joint involvement occurs in 60-84% of cases, primarily in the ankles and knees. Kidney involvement presents as hematuria and/or proteinuria in 5-20% of cases and carries risks for long-term renal issues. GI involvement is seen in 50-80% of cases and can include abdominal pain, bloody diarrhea, and rare complications such as intussusception or perforation.

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    115 views6 pages

    Henoch-Schönlein Purpura (HSP)

    Uploaded by

    Emily Eresuma
    Henoch-Schönlein Purpura (HSP) is the most common vasculitis of childhood that typically occurs between ages 5 and 10 and is thought to be triggered by an infection. It is characterized by IgA deposits that can affect the skin, joints, kidneys, and GI system. Joint involvement occurs in 60-84% of cases, primarily in the ankles and knees. Kidney involvement presents as hematuria and/or proteinuria in 5-20% of cases and carries risks for long-term renal issues. GI involvement is seen in 50-80% of cases and can include abdominal pain, bloody diarrhea, and rare complications such as intussusception or perforation.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
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    Henoch-Schönlein Purpura (HSP)

    •Most common vasculitis of childhood


    •Occurs from childhood – adult
    50% of cases occur under 5
    75% of cases occur under 10
    •Unknown etiology but seasonality suggests
    infectious trigger
    •Known to have IgA deposits effecting
    Skin
    Joint
    Kidney
    GI
    Joint
    • 60-84%
    • Ankles/knees most common
    • Respond well to NSAIDS
    Kidney involvement
    • Occurs in 5-20% of patients
    • Most manifest as hematuria +/- proteinuria
    • Risk factors for significant renal involvement
    – Bloody diarrhea
    – Severe abdominal pain
    – Persistent purpura
    Renal follow up
    • Abnormalities appear within
    – 4 weeks 84%
    – 8 weeks 90%
    – 6 months 97%
    • Follow BP/UA
    • ESRD
    – 15% of those presenting with hematuria/proteinuria
    – 50% who present with nephrotic syndrome
    GI involvement
    • 50-80%
    • Abdominal pain – cramping/colicky – 95%
    • Nausea/Vomiting – 40%
    • Bloody diarrhea 20%
    • % of patients present with abdominal
    symptoms prior to rash 25%
    • Duration of abdominal pain
    GI complications
    • Intussusception
    – Typically ileo-ileo and not reducible via enema
    • Perforation
    • GI hemorrhage

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