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Tinospora Sinesis

Tinospora Sinesis

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Published by 0921py
introduction about Tinospora Sinesis
introduction about Tinospora Sinesis

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Published by: 0921py on Jun 26, 2010
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11/05/2012

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PLANT PROFILE
Tinospora Sinesis
Family : Menispermaceae
Synonymes :
English : Gulancha tinopora, TinosporaHindi : Gulancha. Jungly Giloy, AmritaSanskrit : Guduchi, AmritaMarathi: Gulvel
Distribution :
Throughout India in forests.
Plant:
A large extensively spreading glabours, perennial deciduous twiner withsucculent stems; leaves simple; flowers yellow in lax racemes, male flowers inclusters, female flowers usually solitary; fruits drupes, red when ripe.
Part uses :
Stems, leaves, roots and whole plant.
Properties and uses:
Plant is widely used in Ayurvedic systems of medicine for its general tonic,anti-diabetic, anti-malarial, anti-allergic and aphrodisiac properties. It is alsoclaimed to be useful in skin diseases, vomiting, anaemia, piles, chronic fever andemaciation.
1
 
 
The stem is bitter, stomachic, antipyretic and astringent. It is powderedand made into and infusion, used as alterant. Starch from stem and root (JunglyGiloe Satwa) have nutrient property and is used in chronic diarrhea anddysentery. Juice of tehfresh plant is used as a powerful diuretic and is also usedin gonorrhea. All part of decoction products are mentioned in Ayurvedic textbooks for use in joint diseases. The root is known for its anti-stress, anti-leproticand anti-malarial activities. Various part of plants are shown in fig.
2
 
 
TINOSPORA SINESIS
The chemical examination of stem of 
Tinospora Sinesis
was carried out.The petroleum ether, chloroform, ethanol extracts of the stem were carriedout and their yields were measured.
The alkaloids from the stems of 
Tinospora Sinesis
have been precipitatedwith Dragendorff reagent.
The alcoholic extract of fresh stems of 
Tinospora Sinesis
was found tocontain two bitters (tinosporide and cordifolide), one alkaloid (tinosporin)and
δ
-sitostrol.
Concentrated alcoholic extracts of fresh stems on fractional distillationreported to have three bitter compounds i.e. tinosporon, tinosporic acidand tinosporal and their structures were established by IR absorptionspectra.
Antidiabetic effect of aqueous and alcoholic extracts of the stems of 
Tinospora Sinesis
was reported.
Two compounds were isolated from petroleum ether extract of leaves of 
Tinospora Sinesis
which were identified by TLC on silica gel G plates asoctacosanol and
β
-sitosterol.
From the alcoholic extract of fresh stems,
β
-sitosterol and a compoundnamed tinosporidine have been isolated. Petroleum ether extract of theleaves gave heptacosanol and a carbonyl compound named cordifolone.
Tinosporide, a diterpene isolated from stems of 
Tinospora Sinesis
reported with molecular formula, C
23
H
26
O
8
and structure was assigned onspectral grounds.
3

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