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Cholesterol - good explicadinho

Cholesterol - good explicadinho

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Published by 4gen_4

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Published by: 4gen_4 on Jul 08, 2010
Copyright:Attribution Non-commercial


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Co ro l east Iss What is it?
XWe work for life
What is Cholesterol?
Cholesterol is a fat found only in animalsImportant in Life:
Structure of the human body (cells) Growth Production Reproduction of vi
But excess in the blood can be fatal!
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Where to find the Cholesterol?

Sources of Cholesterol
Made in the body:
primarily by the liver

Animal foods that have cholesterol:Red meat, butter, cheese, poultry skin

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The good and bad cholesterol
Water (blood) and fat (cholesterol) do not mix
Cholesterol is transported in the blood to organs and liver by lipoproteins

LDL (bad cholesterol) at high levels can adhere to artery walls obstructing the passage of blood and clog arteries and cause atherosclerosis, especially in the heart HDL C (good cholesterol) is the cholesterol that helps remove LDL-C in t he body. Its excess protects the heart arteries but its lack is also bad for the body

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Cholesterol - Silent Enemy
Normally High Cholesterol does not cause symptoms in most people.cholestero

l levels high for a long time resulting in atherosclerosis (disease of the arter ies) that leads to heart attacks and strokes. In some people high cholesterol produces some signs called xanthomas and xanthelasma.

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They are an important energy reserve of the body.
They are fats that are elevated in the blood after eating fatty foods.Their
levels are also increased and along with the harmful LDL-C increase the risk of
coronary disease.
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Leading causes of death worldwide
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What is Atherosclerosis?
Is the fat deposits on artery walls, which over time leads to the formation of
a plaque that hampers the passage of blood can lead to a blockage at the site.
This obstruction leads to decreased blood flow to organs with serious conseque

nces for the heart and brain
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Consequences of Atherosclerosis

Angina: chest pain from lack of blood and oxygen Infarction: Death of a piec
e of the heart muscle, for complete lack of circulation and oxygenation at the s
Spill or ischemic stroke: Death of part of brain tissue by complete lack of ci

rculation and oxygenation at the site. Spill or hemorrhagic stroke: The place to form the atherosclerotic plaque can result in a disruption of the vessel in t he brain, causing interruption of blood flow and death of brain tissue at the si te.

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Atherosclerosis is a disease that has many causes and begins in childhood
Atherosclerosis begins in childhood and usually will show up after 55 years of

age in men and 65 women, however, can get ahead! Factors that help in the devel
opment of atherosclerosis • LDL (bad cholesterol high)
• HDL (good cholesterol below) • Older age • Inactivity

• Smoking
• High blood pressure • Diabetes • Obesity
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The sum of the risk factors multiply the risk of Coronary Heart Disease
Incidence of CHD per 1000 people
USA - 1984

200 160 120 80 60 0
Risk Factors:
- Smoking - High Cholesterol - Hypertension
6X More
One factor Two factors All three factors
Source - Department of Health of the United States of America. We work for life
Why control the risk factors?

Control cholesterol = - 33% of heart attack risk - 25% risk of death - 20% ris

k of stroke. Control of blood pressure = 15% of heart attack risk - 42% risk o f stroke Stop smoking = - 50% of heart attack risk - 70% risk of death. Lose weight and exercise = - 25% risk of diabetes Important: who has diabetes has

a risk about four times more likely to die of cardiovascular disease.
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Progression and Impact of Cardiovascular Disease
Clinical Consequences:
Myocardial Infarction
Left Ventricular Hypertrophy
Heart Failure
Peripheral Vascular Disease
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Is it possible to adequately prevent atherosclerosis?

To prevent atherosclerosis is necessary to identify who is at risk of having t

his disease. This is very easy, just a doctor's appointment, For the patient 's history and physical examination and simple blood tests can make the diagnosi s and assess the risk of atherosclerosis

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Who is at risk for myocardial infarction and death from heart disease?
Anyone who has had stroke, obstruction of arteries in the legs or who are diab

etic aorta Who has high cholesterol who already had heart attacks, angina, made of bypass surgery or angioplasty Who is familiar with infarction or sudd en death

Sedentary, overweight, smoker
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Why is it important to Reduce High Cholesterol

10% reduction
15% reduction in CHD
11% reduction in mortality
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Treatment goals

Prevent Coronary Heart Disease Mortality Prevent Preventing Complications:
Infarction, Stroke, Impotence, angina (chest pain)
Improving quality of life.see their grandchildren grow.

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