Insulin Onset Peak Duration Info

Lispro 15-30 mins 0.5-2.5 h 6-8 h SubQ

Regular 10-30 mins 1-5 h 6-10 h
**Can Mix others c
this Insulin
NPH 60-120 mins 6-14 h 16-24 h
**NPH most common
cause of Reactions
give PROTAMINE
antidote & NPH is
ONLY given via SUB-
Q route

Lente 60-180 mins 6-14 h 16-24 h Contains ZINC

Ultralente 240-360 mins 8-20 h 24-48 h Contains Zinc
Glargine 70 mins NO PEAK 24 h
NO MIXING THIS c
ANYTHING!! Given
Q Daily c Basal
Dosing

REGULAR insulin: is used for IV Administration

Rolling in b/w the palms: is the techniques used to mix Insulin preparations

When Mixing Regular & NPH together, the appropriate steps are:

1. AIR in NPH vial

2. AIR in Regular vial
3. Draw up Regular dose (get rid of air Bubbles!)
4. Draw up NPH dose

Glargine may not be mixed in the same syringe c other insulin  TRUE!!!

INSULIN ADMINISTRATION SITE:

1. ABD (BEST place quick absorption)
2. Tricep area behind arm
3. anterior Thigh

SE’s of Insulin: Rash, hardness, itching, RESP Distress pt can overcome these by giving themselves insulin in smaller doses.

Short acting insulin  CLEAR

Long acting insulin  CLOUDY
REM: b/c CLEAR takes on the characteristics of the cloudy insulin, if the cloudy gets into the clear vial, the clear vial will NO LONGER
BE PURE!

CLEAR CLOUDY
AIR into VIAL
AIR into VIAL
DRAW UP dose
DRAW UP dose
**per Lehne, pg 670 All Insulins c exception of NPH, are formulated to be clear, colorless solutions and hence can be administered c out
resuspension