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Patho Edited

Patho Edited

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Published by Erick Vladd

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Published by: Erick Vladd on Aug 29, 2010
Copyright:Attribution Non-commercial

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05/22/2012

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Pathophysiology of Diabetes Mellitus Type II
 
Precipitating factors:
1.development of glucoseintolerance during drug therapy2.GDM3.sedentary lifestyle4.stress5.obesity6.decrease serum potassium7.Toxin/Virus
Predisposing factors:
1.
family history of DM/Genetic2.Age above 403.Race4.Gende
Idiopathic
Insufficient insulin-receptor on theinsulin-dependent cells (liver cells, muscles and fats)Impaired beta cell function andinsulin secretionReduced hepaticinsulin sensitivityBody does not respond tothe action of insulin (InsulinResistance)Decreased insulin productionReduced tissue uptake of glucoseLiver senses lowglucose levelLiver convertsGlycogen to glucoseand releasing it tothe Blood
A
 
B

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