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Schistosoma - cirrhosis patho

Schistosoma - cirrhosis patho

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Published by duzlly

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Published by: duzlly on Sep 01, 2010
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05/25/2012

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Pathophysiology Diagram:Predisposingfactors:EnvironmentPrecipitatingfactors:AlcoholismContact with infestedSchistosomal cercaria attachto the skin and penetrate Transformation from a free-livinginfective stage to a parasitic larvalOnce through the dermis, they locateschistosomula are carried to the first capillary bed, thelungs, where they become lodged and double in size The larvae then make their way to theWorms mature and paired adults migrate out of theliver to the mesenteries where the female begins laying The eggs pass through the walls of the mesenteriesand through the intestinal walls into the gut lumen andNot all the eggs pass out via the intestine. Manyof the eggs are swept back to the liver whereLodged in the liverhost inflammatoryresponse activates inEggs become surrounded by a dense infiltrate composed of mainlylymphocytes, macrophages and a variable number of eosinophils, heldLarge florid lesions are produced as an earlyRelease of SEA - soluble egg
skin rashes
asthma-likeepisodes
fever
malaise
diarrhea
swollen lymphnodesHepatocyte
Fever
Pain
Anorexia
Fatigue
Nausea andvomiting

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