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WHO Rapid AI Treatment

WHO Rapid AI Treatment

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Published by: gunmahameru on Sep 22, 2010
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WHO Rapid Advice Guidelineson pharmacologicalmanagement of humansinfected with avian influenza A(H5N1) virus
© World Health Organization 2006
All rights reserved. Publications of the World Health Organization can be obtained from WHO Press,World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264;fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce ortranslate WHO publications – whether for sale or for noncommercial distribution – should beaddressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail:permissions@who.int).The designations employed and the presentation of the material in this publication do not imply theexpression of any opinion whatsoever on the part of the World Health Organization concerning thelegal status of any country, territory, city or area or of its authorities, or concerning thedelimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border linesfor which there may not yet be full agreement.The mention of specific companies or of certain manufacturers’ products does not imply that theyare endorsed or recommended by the World Health Organization in preference to others of asimilar nature that are not mentioned. Errors and omissions excepted, the names of proprietaryproducts are distinguished by initial capital letters.All reasonable precautions have been taken by the World Health Organization to verify theinformation contained in this publication. However, the published material is being distributedwithout warranty of any kind, either expressed or implied. The responsibility for the interpretationand use of the material lies with the reader. In no event shall the World Health Organization beliable for damages arising from its use.
Executive summary iSummary of clinical recommendations vii1 Background 12 Scope 33 Methods 54 Case description
Assessment of possible casesCase description/clinical features
 5 Treatment of H5N1 patients
OseltamivirZanamivirAmantadineRimantadineCombination treatment
 6 Chemoprophylaxis of H5N1 infection
 7 Co-interventions for the management of H5N1patients
Prophylactic antibioticsSteroids and other immunosuppressantsImmunoglobulinRibavirin
 8 Antiviral drug supply 439 Priorities for revision of the guidelines 4510 Priorities for research 47

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