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Table Of Contents

1. INTRODUCTION
1.1 Background
1.2 Objectives and target audience
1.3 Methods used in developing the guidelines and recommendations
2. CLINICAL DISEASE AND EPIDEMIOLOGY
3. OBJECTIVES OF TREATMENT
3.1 Uncomplicated malaria
3.2 Severe malaria
4. RESISTANCE TO ANTIMALARIAL MEDICINES
4.1 Impact of resistance
4.2 Global distribution of resistance
4.3 Assessing efficacy and resistance
5. ANTIMALARIAL TREATMENT POLICY
5.1 Criteria for antimalarial treatment policy change
5.2 Therapeutic efficacy cut-offs for changing treatment policy
6. DIAGNOSIS OF MALARIA
6.1 Clinical diagnosis
6.2 Parasitological diagnosis
6.3 Where malaria transmission is low-to-moderate and/or unstable
6.4 In stable high-transmission settings
6.5 Malaria parasite species identification
6.6 In epidemics and complex emergencies
7. TREATMENT OF UNCOMPLICATED P. FALCIPARUM MALARIA
7.1 Definition of uncomplicated malaria
7.2 Rationale for antimalarial combination therapy
7.3 ACT options
7.4 Management of treatment failures
7.5 Practical aspects of treatment with recommended ACTs
7.6 Incorrect approaches to treatment
7.7 Additional considerations for clinical management
7.8 Operational issues in treatment management
7.9 Treatment in specific populations and situations
7.10 Co-existing morbidities
8. TREATMENT OF SEVERE P. FALCIPARUM MALARIA
8.1 Definition
8.2 Treatment objectives
8.3 Clinical assessment
8.4 Specific antimalarial treatment
8.5 Follow-on treatment
8.6 Pre-referral treatment options
8.7 Practical aspects of treatment
8.8 Adjunctive treatment
8.9 Continuing supportive care
8.10 Additional aspects of management
8.11 Treatment of severe malaria in special groups during pregnancy
9. TREATMENT OF MALARIA CAUSED BY P. VIVAX, P. OVALE OR P. MALARIAE
9.1 Diagnosis
9.2 Susceptibility of P. vivax, P. ovale and P. malariae to antimalarials
9.3 Treatment of uncomplicated vivax malaria
9.4 Treatment of severe P. vivax malaria
9.5 Treatment of malaria caused by P. ovale and P. malariae
9.6 Monitoring therapeutic efficacy for vivax malaria
10. MIXED MALARIA INFECTIONS
11. COMPLEX EMERGENCIES AND EPIDEMICS
11.1 Diagnosis
11.2 Management of uncomplicated falciparum malaria
11.3 Areas prone to mixed falciparum/vivax malaria epidemics
11.4 Areas prone to vivax malaria epidemics
11.5 Anti-relapse therapy in vivax malaria epidemics
11.6 Management of severe falciparum malaria
12. CASE MANAGEMENT IN THE CONTEXT OF MALARIA ELIMINATION
12.1 Use of gametocytocidal drugs to reduce transmission
12.2 Mass screening and treatment
13. MASS DRUG ADMINISTRATION
13. Mass drug administration
THE GUIDELINES DEVELOPMENT PROCESS
PHARMACOLOGY OF ANTIMALARIAL MEDICINES
RESISTANCE TO ANTIMALARIAL MEDICINES
INDEX
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9789241547925_eng

9789241547925_eng

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Published by Pallab Biswas

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Published by: Pallab Biswas on Oct 06, 2010
Copyright:Attribution Non-commercial

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05/19/2012

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