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Leprosy

Leprosy

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Categories:Types, School Work
Published by: bernard allan mabanto on Oct 07, 2010
Copyright:Attribution Non-commercial

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06/07/2013

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M.YousryM.YousryTB&leprosyTB&leprosy11
Cutaneous leprosyCutaneous leprosy
Leprosy is a chronic granulomatousdisease, caused by
Mycobacteriumleprae,
w
hich affects principally theskinandperipheral nervous system
A
nimal reservoirs of leprosy : 9-bandedarmadillos & chimpanzees
 
M.YousryM.YousryTB&leprosyTB&leprosy22
P
athophysiology:
P
athophysiology:
The areas most commonly affected by leprosyare the
superficial peripheral nerves
,
 skin
,
mucous membranesof the upper respiratorytract
,
anterior chamber of theeyes
,
andtestes.
Th
ese areas tend to be cooler parts of t 
h
ebody 
.Tissue damage is caused by the degree towhichcell-mediated immunityis expressed
,
theextent of bacillary spreadandmultiplication
,
theimmunologic complications(ie
,
lepra reactions)
,
 and thenerve damageand itssequelae
 
M.YousryM.YousryTB&leprosyTB&leprosy33
M leprae
is an obligate intracellular acid-fast bacillus
w
ith a unique ability to enter nerves.The incubation period ranges from 6months to 40 years or longer. The averageincubation period is 2-3 years.

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