Welcome to Scribd, the world's digital library. Read, publish, and share books and documents. See more
Download
Standard view
Full view
of .
Look up keyword
Like this
3Activity
0 of .
Results for:
No results containing your search query
P. 1
Ichthyosis

Ichthyosis

Ratings: (0)|Views: 194|Likes:
Published by Bahaa Mostafa Kamel

More info:

Categories:Types, School Work
Published by: Bahaa Mostafa Kamel on Oct 17, 2010
Copyright:Attribution Non-commercial

Availability:

Read on Scribd mobile: iPhone, iPad and Android.
download as PPT, PDF, TXT or read online from Scribd
See more
See less

11/10/2012

pdf

text

original

 
Genodermatosis
By Dr. Nouran abou khedr 
 
Xeroderma Pigmentosum
Xeroderma pigmentosum is a rare disorder transmitted in an autosomal recessivemanner. It is characterized by photosensitivity,pigmentary changes, premature skin aging,and malignant tumor development .Thesemanifestations are due to a cellular hypersensitivity to ultraviolet (UV) radiationresulting from a defect in DNA repair.
 
Pathophysiology
The basic defect in xeroderma pigmentosum isin nucleotide excision repair (NER), leadingto deficient repair of DNA damaged by UVradiation.
Mortality/Morbidity
Individuals with this disease develop multiplecutaneous neoplasms at a young age. Twoimportant causes of mortality are metastaticmalignant melanoma and squamous cellcarcinoma

Activity (3)

You've already reviewed this. Edit your review.
1 thousand reads
1 hundred reads

You're Reading a Free Preview

Download
scribd
/*********** DO NOT ALTER ANYTHING BELOW THIS LINE ! ************/ var s_code=s.t();if(s_code)document.write(s_code)//-->