DNA Timeline Activity

http://www.dnai.org/timeline/index.html

Use the information on this website to complete the questions below.

1. Go to Avery and the transforming factor. Click through the information on Avery until
you get to the description of Fred Griffith. The first experiment described is the Griffith
experiment. Outline the procedure that Griffith did and what was his conclusion?

2. Describe the Hershey-Chase experiment (you will have to click on the early 50’s tab at
the bottom of the webpage):

3. What did Chargaff discover? What are Chargaff’s rules?

4. What is Rosalind Franklin famous for?

5. Go to the Watson and Crick experiment:
a. What is a nucleotide?

b. List the 4 nitrogenous bases:

c. What comprises a nucleotide?

d. What two things helped Watson and Crick solve the puzzle of the structure of
DNA:

e. What types of bonds hold the nucleotides together?

f. List the nitrogenous bases that have 2 carbon rings. List the two nitrogenous
bases that only have 1 carbon ring.

g. How many hydrogen bonds does adenine make with thymine? How many
hydrogen bonds does guanine make with cytosine?

h. Describe the double helix based on the twisted ladder analogy:

6. Go to the year 2000 tab at the bottom of the webpage. What are Craig Venter and
Francis Collins famous for?