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Table Of Contents

CHAPTER 1 THE SCOPE OF BIOCHEMISTRY
Biochemistry is a Contemporary Science
Extrapolating Biochemical Information
Common Themes in Biochemistry
Biochemical reactions involve small molecular structures
Polymers in Living Systems
Cell membranes
Types of Biochemical Reactions
Regulating biochemical reactions
Large molecules provide cell information
Weak interactions and structural stability
Biochemical reactions occur in a downhill fashion
All Organisms are Related
The Common Origin of Organisms
The United Strength of Biochemical Structures
Properties of Water and Biomolecular Structure
The Hydrophobic Effect
Nonpolar molecules and water-solubility
Membrane associations
Electrostatic and van der Waals Interactions
Acid-Base Reactions in Living Systems
pK values and protonation
Solution pH
Buffer capacity
Biological acid-base equilibria
Types of Metabolic Reactions
Enzyme Catalysts
Space and Time Links in Metabolic Reactions
Energy Flow
Free Energy Calculations
The Cell’s Energy Currency
Free-Energy-Driven Transport across Membranes
Complexity in Biochemical Genetics
DNA,RNA,and nucleotide structure
The DNA double helix and genetic replication
RNA Carries Genetic Information
Transfer RNA
Base-Pairing and the Central Dogma
Genetic information expression
CHAPTER 5 PROTEIN STRUCTURE
Levels of Protein Structure
Amino acids
Amino acid side chains
Primary structure
Secondary structure
Fibrous and globular proteins
Tertiary structure
Protein-assisted folding
Quaternary structures
The Chemistry of Molecular Oxygen
Hemoglobin and myoglobin
Myoglobin binds oxygen
Binding oxygen to hemoglobin
Physiological conditions and hemoglobin
Acidic conditions and hemoglobin
Temperature
Fetal hemoglobin
CHAPTER 7 ENZYMES
Enzymes Are Catalysts
Six Types of Enzyme Catalysts
The Michaelis-Menten equation
Inhibitors of enzyme-catalyzed reactions
Chemical Mechanisms of Enzyme Catalysis
The transition state
Vitamin conversion
Chymotrypsin:An Enzyme at Work
Enzyme Regulation
Covalent Modification
Phosphorylation
Zymogens
CHAPTER 8 ORGANIZATION OF METABOLISM
Energy production
Catabolic pathways feed into the TCA cycle
Biosynthetic reactions versus catabolic reactions
CHAPTER 9 GLYCOLYSIS
Six-Carbon Reactions
Electron transfer to pyruvate
Ethanol
Glycolysis Regulation
Glycolysis produces short but high bursts of energy
CHAPTER 10 THE TRICARBOXYLIC ACID CYCLE
The First Phase of the TCA Cycle
Oxidative decarboxylation
Substrate Availiability,Pyruvate,and the TCA Cycle
CHAPTER 11 OXIDATIVE PHOSPHORYLATION
Oxidative Phosphorylation
The energy of oxidation
The oxidation of NADH
ATPSynthesis
Mitochondrial Transport Systems
Energy Yields from Oxidative Phosphorylation
CHAPTER 12 CARBOHYDRATE METABOLISM II
The Pentose Phosphate Pathway
Ribulose-5-phosphate
Converting pentoses to sugars
Catabolism of other carbohydrates
Bypassing the pyruvate kinase step
Storage of Glucose in Polymeric Form as Glycogen
Cyclic AMP
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37977968 Biochemistry

37977968 Biochemistry

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Published by: KrupaBaby on Nov 12, 2010
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11/06/2011

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