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Erythromycin

Erythromycin

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Published by FrozanS

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Published by: FrozanS on Nov 29, 2010
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01/29/2013

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DRUG STUDY
 PART 1: to be completed prior to clinical experience.
Generic Name:
erythromycin
Dosage Range:
2% ointment (
Topical
Apply 0.5–1 cmribbon in lower conjunctival sacs shortly after birth)
Trade Name(s):
Apo-Erythro Base
(Canadian)
A/T/S
 
E-Mycin
 
Eryc
 
EryDerm
 
EryTab, Erythrocin
 
Erythromid
(Canadian)
Erythromycin Base
 
Novorythro
(Canadian)
PCE
 
Ro-Mycin
(Canadian)
Classification:
MACROLIDE ANTIBIOTIC
Action of Medication
(in 1-2 sentences using your own words):
More active against gram-positive organisms than against gram-negative organisms due to its superior penetration into gram-positive organisms.
Therapeutic Uses
(in 1-2 sentences using your own words):
Pyodermas, acne vulgaris, and external ocular infections, including neonatal chlamydialconjunctivitis and gonococcal ophthalmia.
Common Side Effects or Adverse Effects
GI:
 Nausea, vomiting, abdominal cramping,
diarrhea, heartburn, anorexia.
Body as a Whole:
Fever, eosinophilia, urticaria, skin eruptions, fixed drug eruption,anaphylaxis. Superinfections by nonsusceptible bacteria, yeasts, or fungi.
Special Senses:
Ototoxicity: reversible bilateral hearing loss, tinnitus, vertigo.
Digestive:
(Estolate) Cholestatic hepatitis syndrome.
Skin:
(topical use) Erythema, desquamation, burning, tenderness, dryness or oiliness, pruritus.
 
Nursing Responsibilities
Food: Grapefruit juice
may increase side effects.
Report onset of GI symptoms after PO administration to physician. These are doserelated; if symptoms persist after dosage reduction, physician may prescribe drug to begiven with meals in spite of impaired absorption.
Observe for S&S of superinfection by overgrowth of nonsusceptible bacteria or fungi.Emergence of resistant staphylococcal strains is highly predictable during prolongedtherapy.
Monitor for S&S of hepatotoxicity. Premonitory S&S include: Abdominal pain, nausea,vomiting, fever, leukocytosis, and eosinophilia; jaundice may or may not be present.Symptoms may appear a few days after initiation of drug but usually occur after 1–2 wk of continuous therapy. Symptoms are reversible with prompt discontinuation of erythromycin.
Monitor for ototoxicity that appears to develop most frequently in patients receiving 4 g/dor more, older adults, female patients, and patients with kidney or liver dysfunction. It isreversible with prompt discontinuation of drug.
Report any ototoxic effects including dizziness, vertigo, nausea, tinnitus, roaring noises,hearing impairment
 
DRUG STUDY
 PART 1: to be completed prior to clinical experience.
Generic Name:
hydromorphone hydrochloride
Dosage Range:
PO
2–4 mg q4–6h prn in naïve patients
SC/IM/IV
0.75–2 mg q4–6h depending on patient response
Trade Name(s):
Dilaudid
 
Classification:
 NARCOTIC (OPIATE) AGONIST;ANALGESIC
Action of Medication
(in 1-2 sentences using your own words):
 An effective narcotic analgesic that controls mild to moderate pain. Also has antitussive properties.
Therapeutic Uses
(in 1-2 sentences using your own words):
Relief of moderate to severe pain and control of persistent nonproductive cough.
Common Side Effects or Adverse Effects
CNS:
Euphoria, dizziness, sedation,
drowsiness
CVS:
Hypotension, bradycardia or tachycardia
GI:
 Nausea, vomiting, constipation
Respiratory:
Respiratory depression
Hypersensitivity:
Blurred vision
Nursing Responsibilities
 Note baseline respiratory rate, rhythm, and depth and size of pupils before administration.Respirations of 12/min or less and mitosis are signs of toxicity. Withhold drug and promptly notify physician.
Monitor vital signs at regular intervals. Drug-induced respiratory depression may occur even with small doses and increases progressively with higher doses.
Assess effectiveness of pain relief 30 min after medication administration.
Monitor drug effects carefully in older adult or debilitated patients and those withimpaired renal and hepatic function.
Assess effectiveness of cough. Drug depresses cough and sigh reflexes and may induceatelectasis, especially in postoperative patients and those with pulmonary disease.
 Nausea and orthostatic hypotension most often occur in ambulatory patients or when asupine patient assumes the head-up position.
Monitor I&O ratio and pattern. Assess lower abdomen for bladder distension. Reportoliguria or urinary retention.
Monitor bowel pattern; drug-induced constipation may require treatment
Use caution with activities requiring alertness; drug may cause drowsiness, dizziness, and blurred vision.

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