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Table Of Contents

1 AN INTRODUCTION TO MICRORNAS
1.1 microRNA biogenesis
1.2 microRNA function
1.3 Methods for microRNA target prediction
1.4 microRNA discovery, detection and profiling
1.5 Perspectives and research goals
1.6 References
and discovery in human embryonic stem cells
2.1 List of Authors
2.2 Introduction
2.3 Results
2.3.1 Sequencing and annotation of small RNAs
2.3.2 Variability in microRNA processing
2.3.3 Enzymatic modification of microRNAs
2.3.4 MicroRNAs differentially expressed between hESCs and EBs
2.3.5 Novel microRNA genes
2.3.6 Targets of differentially expressed microRNAs
2.4 Discussion
2.5 Methods
2.5.1 Small RNA Library Preparation
2.5.2 Small RNA Genome Mapping and Quantification
2.5.3 Differential Expression Detection
2.5.4 Small RNA annotation
2.5.5 Novel microRNA detection
2.5.6 Cooperative miRNA target prediction
2.5.7 Gene Ontology analysis
2.6 References
3 CONCLUDING REMARKS
3.1 Goals accomplished
3.2 Future directions
3.3 References
APPENDICES Appendix A: Supplementary Tables
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MicroRNA Profiling and Discovery

MicroRNA Profiling and Discovery

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Published by Chintan Vora

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Published by: Chintan Vora on Dec 01, 2010
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11/08/2011

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