Knowing what specific nutrients can boost muscle glycogen stores can improve anathlete’s performance. Morifuji
fed male Sprague-Dawley rats eitherglucose alone, glucose + whey protein, glucose + whey protein hydrolysate,glucose + casein hydrolysate or glucose + branched chain amino acids immediatelyafter a glycogen-depleting exercise. Only the rats given the glucose + whey proteinhydrolysate had significant increases in skeletal muscle glycogen levels comparedto the other protein sources or BCAA.Using rat L6 myotubes, Morifuji
(12) showed that branched chain amino acid-containing di-peptides in whey protein hydrolysate (Ile-Leu, Leu-Val, Val-Leu, Ile-Ile, Leu-Ile, Ile, Leu) significantly stimulated glucose uptake using an
model. These researchers also demonstrated that the main di-peptide in wheyprotein hydrolysate (Ile-Leu) stimulated glucose uptake in rat isolated epitrochlearismuscles.Therefore, whey protein hydrolysate enhances the effects of carbohydrate ingestionon post-exercise muscle glycogen resynthesis for both
Insulin Secretion And Skeletal Muscle Anabolism
The most important trigger for insulin secretion is glucose. However, secretion of insulin can be induced by amino acids as well. Leucine is a potent insulintropicmolecule, but recent evidence suggests that a rise in glucose concentration isnecessary for leucine to stimulate significant insulin secretion (13).Additional research has shown that insulin-induced increase in muscle proteinanabolism is age dependent. In young adults, insulin is mainly permissive ratherthan stimulatory for muscle protein anabolism, whereas in older adults super highlevels of insulin appear to be necessary to stimulate muscle protein anabolism (14).To learn more about PROGENEX’s high-quality whey protein hydrolysates visitwww.progenexusa.com
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Protein hydrolysates in sports nutrition.
Nutr & Metab 2009,6:38-43.2. Grimble GK.
The significance of peptides in clinical nutrition.
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