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David A. Steenblock, D.O.

Inc
Personalized Regenerative Medicine

ADULT STEM CELLS HEAL THE GUT


Stem Cell Therapy for Treatment of Chrons, Ulcerative Colitis & IBD

Crohn’s disease, together with ulcerative colitis, is included in what is called irritable
bowel disease. It is a chronic genetic disease that occurs when the immune system loses
tolerance to the patient’s own intestinal flora, leading to an abnormal inflammatory
response that continues over time. The results are inflammation and ulceration in
different areas of the digestive tract, leading to the symptoms. The disease progresses in
the form of unpredictable and variable outbreaks throughout the patient’s life and the
severity of the symptoms varies according to the level of involvement of the intestines
and the patient’s response to the assigned treatment.

It is a disease that usually affects young people between the ages of 18 and 40 years, and
approximately 2000 new cases are diagnosed in Spain every year. Diagnosis is often
difficult because it presents symptoms similar to those of other diseases of the digestive
tract: abdominal pain, diarrhea, vomiting, nausea, fever, general malaise, etc. Patients’
quality of life is conditioned by the severity of the disease and, in the most severe cases,
prevents them from leading a normal life, with a very high level of suffering due to the
acuteness and frequency of the intestinal symptoms.

In severe cases involving recurrent outbreaks (reactivation of the disease several times
throughout the patient’s life), Crohn’s disease presents several treatment options. Firstly,
doctors choose to use corticosteroids and immunosuppressant and biological drugs to
control the inflammatory process and prevent complications of the disease such as
stenosis (narrowing of the intestinal lumen) or fistulas (openings from the intestinal
lumen to other organs, such as the intestine, bladder, vagina, or skin). However, over the
course of the disease, as much as 70% of severe patients require surgery to remove
segments affected by the disease, due to failure of the pharmacologic approach. The
surgery is occasionally very aggressive for the patient, as it is sometimes necessary to
remove the entire colon or large sections of the small intestine, thereby considerably
affecting the absorption of food by the intestine, with a resulting deterioration in quality
of life and body image (colostomy bag). For this reason, new treatments are being
developed for patients in whom this solution has not been an option to date.

Cellular therapy with stem cells is revolutionizing the focus of treatment of many
serious diseases. Replacing the cells of damaged tissue with other new cells from the
same patient is already a reality. This is the basis of cellular therapy and regenerative
medicine, the latest great advance in biomedicine.

The procedure is based on an autologous bone-marrow transplant (when patients


receive a transplant of their own stem cells) and now constitutes a treatment option to
cure an intestinal disease that sometimes does not successfully respond to drugs and
requires highly complex surgery that does not provide a cure.

With this therapy, in an average follow-up period of 6 years, 80% of transplant patients
are in a phase of total remission of the disease and the remaining 20% have shown
considerable improvement following the transplant, and are now responding favorably to
drugs.

Of course, no one here in North America needs to travel abroad to obtain autologous
bone marrow treatments, as this is legally available right here at “Dr. Steenblock’s
Clinic.” In addition, Dr. Steenblock has done over 1,000 such bone marrow procedures
during the past six years. Along the way he has discovered that when specific FDA stem
cell activators are used prior to and following these, patient healing responses go up
dramatically.

Tel:(949) 367-8870 ~ Fax:(949) 367-9779 ~ Toll Free: 1-800-900-1063


26381 Crown Valley Parkway, Suite 130 ~ Mission Viejo, California 92691 ~ WWW.STEMCELL.MD

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