UNIT TWO: CELL BIOLOGY(Text from Modern Biology, Holt, Rinehart, and Winston)2Between cell divisions, DNA is not so tightly coiled. Regions of DNA uncoil sothey can be read and the information can be used to direct cell activity. The lesstightly coiled DNA-protein complex is called chromatinchromatinchromatinchromatin.In most prokaryotes, the DNA consists of only one chromosome, a circular DNAmolecule, attached to the inside of the cell membrane.CHROMOSOME NUMBERSEach species have a characteristic number of chromosomes found in each cell.Some species have the same number of chromosomes. Humans have 46chromosomes in each cell.Sex Chromosomes and AutosomesHuman and animal chromosomes are categorized as either sex chromosomesor autosomes. Sex chromosomesSex chromosomesSex chromosomesSex chromosomes determine the sex of an organism, and may alsocarry genes for other characteristics. In humans, sex chromosomes are either X or Y.Females have two X chromosomes, and males have an X and Y chromosome. All of theother chromosomes in an organism are classed as autosomesautosomesautosomesautosomes.Every cell of an organism produced by sexual reproduction has two copies of each autosome, one from each parent. The two copies of each autosome are calledhomologous chromosomeshomologous chromosomeshomologous chromosomeshomologous chromosomes, or
homologues
. They are the same size and shape andcarry different genes for the same trait. For example, if one chromosome in a pair of homologues contains a gene for eye color, so will the other one. However, the genesare not necessarily identical. One gene may code for blue eyes and the other forbrown eyes.A karyotypekaryotypekaryotypekaryotype is a photomicrograph of the chromosomes in a normal dividing cell found in a human. 46 human chromosomes exist as 22 homologous pairs of autosomesand two sex chromosomes (XY for males and XX for females).Diploid and Haploid CellsCells with two sets of chromosomes are diploiddiploiddiploiddiploid, and have two autosomes foreach homologous pair. Diploid cells also have two sex chromosomes in animals, and inmany other organisms that have sex chromosomes. Diploid is commonly abbreviatedas 2
n
. In humans, the 2
n
number of chromosomes is 46 – 22 pairs of homologousautosomes and 2 sex chromosomes.Sperm and egg cells are haploidhaploidhaploidhaploid cells, which contain only one set of chromosomes. Haploid cells (1
n
) have only one autosome of each homologous pair andonly one sex chromosome; ergo, the haploid cells of humans have 23 chromosomes.When a sperm cell (1
n
) and an egg cell (1
n
) combine to create the first cell of a neworganism, the new cell will be diploid (2
n
). If the reproductive cells were diploid, thenew cell would have too many chromosomes.
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